Evidence map›Paper›PMID 40899268›Full record

ArticleAnnals of laboratory medicine2026

Diagnostic Accuracy of Serological Tests for

Gahee Kim, Ki Wook Yun, Dayun Kang, Taek Jin Lee, Byung Wook Eun, Hyunju Lee, Yae-Jean Kim, Doo Ri Kim, Areum Shin, Hyun Mi Kang and 12 more

Abstract read
In one paragraph

Article in Annals of laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Analysis of influenza A, influenza B andFrontiers in public health · 2026
    Article
  4. Growing Threat of Macrolide-ResistantJournal of Korean medical science · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Gahee KimDepartment of Pediatrics, Chosun University Hospital, Chosun University College of Medicine, Gwangju, Korea.ORCID https://orcid.org/0000-0002-2594-6543
Ki Wook YunDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0798-6779
Dayun KangDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-0314-9455
Taek Jin LeeDepartment of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Korea.ORCID https://orcid.org/0000-0002-8912-6982
Byung Wook EunDepartment of Pediatrics, Eulji University Eulji General Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-3147-9061
Hyunju LeeDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0107-0724
Yae-Jean KimDepartment of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyungwan University, Seoul, Korea.ORCID https://orcid.org/0000-0002-8367-3424
Doo Ri KimDepartment of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyungwan University, Seoul, Korea.ORCID https://orcid.org/0000-0001-5233-4043
Areum ShinDepartment of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyungwan University, Seoul, Korea.ORCID https://orcid.org/0000-0003-3341-0447
Hyun Mi KangDepartment of Pediatrics, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0513-8407
Ye Ji KimDepartment of Pediatrics, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0009-4611-455X
Byung Ok KwakDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5527-0794
Younghee LeeDepartment of Pediatrics, Kangwon National University Hospital, Chuncheon, Korea.ORCID https://orcid.org/0000-0001-8990-4273
Ye Kyung KimDepartment of Pediatrics, Konkuk University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-7145-8738
Young June ChoeDepartment of Pediatrics, Korea University Anam Hospital, and Allergy and Immunology Center, Korea University, Seoul, Korea.ORCID https://orcid.org/0000-0003-2733-0715
Woosuck SuhDepartment of Pediatrics, Daejeon St. Mary's Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0002-7730-5772
Kyo Jin JoDepartment of Pediatrics, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.ORCID https://orcid.org/0000-0002-4947-3672
Kyung-Ran KimDepartment of Pediatrics, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.ORCID https://orcid.org/0000-0003-2557-3000
Eun Young ChoDepartment of Pediatrics, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-2286-4593
Kyung Min KimDepartment of Pediatrics, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-7888-2459
Joon Kee LeeDepartment of Pediatrics, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0001-8191-0812
Su Eun ParkDepartment of Pediatrics, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.ORCID https://orcid.org/0000-0001-5860-821X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: From September 2023 to September 2024, we prospectively enrolled children with CAP, classified as Results: Among 472 children with CAP (362 MPP, 110 non-MPP), 138 (29.2%) underwent PA testing, and 334 (70.8%) underwent IgM testing. PA at a 1:640 cutoff showed 48.0% sensitivity and 100% specificity. CLIA and ELISA showed comparable sensitivities (69.1% vs. 69.2%) and specificities (76.9% vs. 66.7%) for IgM testing. Seropositivity increased significantly with time since symptom onset ( Conclusions: The time post-symptom onset significantly influenced the diagnostic utility of serological tests for pediatric MPP, which showed limited value during the early stage of illness. These findings emphasize the importance of symptom onset-based interpretation of serological test results and their utility in complementing PCR when optimizing MPP diagnosis in children.

Indexed as

Mycoplasma pneumoniaePneumonia, MycoplasmaSerologic TestsAntibodies, BacterialChildChild, PreschoolCommunity-Acquired InfectionsEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GImmunoglobulin MInfantLuminescent MeasurementsMaleProspective StudiesAntibodies, BacterialImmunoglobulin GImmunoglobulin MChildCommunity-acquired pneumoniaSerology

Identifiers

PMID40899268
PMCPMC12915381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.