Evidence map›Paper›PMID 40899213›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2025

[Clinical efficacy of demineralized dentin matrix particles in immediate implantation for bone defects in posterior region: a 1 to 5-year follow-up study].

Hao Wu, Ning Cao, Liangwei Cao, Fei Yu, Xu Zhang, Shibo Wei, Hongwu Wei, Shuigen Guo

Abstract readEnglish Abstract
In one paragraph

Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hao WuDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Ning CaoDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Liangwei CaoDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Fei YuDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Xu ZhangDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Shibo WeiDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Hongwu WeiDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.
Shuigen GuoDept. of Stomatology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the short- to medium-term clinical efficacy of demineralized dentin matrix (DDM) particles applied during the immediate implantation of alveolar bone defects in the posterior region.

methodsA total of 76 patients with 110 simple taper retentive implants were included in the conducted study and divided into Groups A and B in accordance with the bone grafting materials. Cone beam computed tomography and panoramic radiographs were taken immediately after implant surgery, immediate crown repair, and final follow-up time. The average follow-up time for Groups A and B was recorded. The primary observed clinical indicators were overall survival rate of the implant, bone resorption of the mesial and distal margins of the implant, buccal bone width resorption at the platform level and 1 mm below the platform, and bone height of the implant. Implant complication was a secondary observed clinical indicator.

resultsDuring the 1-to-5-year follow-up observation period, the mean follow-up of Group A was 38.2 months while that of Group B was 39.9 months. In Group A, two implants failed, one of which fractured, and implant overall survival rate was 96.4%. Four implants failed in Group B due to peri-implantitis, and implant overall survival rate was 92.6%. No statistically significant difference in implant overall survival rate was found between the two groups (

conclusionsDuring the 1-to-5-year follow-up observation period, DDM particles can effectively increase the height and width of alveolar bone, and they can achieve the same effect of maintaining alveolar bone contour and bone augmentation compared with deproteinized inorganic calf bone. DDM particles can be used as a potential new bone grafting material for the treatment of bone defects in clinical practice.

Indexed as

Bone TransplantationDental ImplantsDentinAdultAlveolar Bone LossCone-Beam Computed TomographyDental Implantation, EndosseousFemaleFollow-Up StudiesHumansImmediate Dental Implant LoadingMaleMiddle AgedRadiography, PanoramicRetrospective StudiesDemineralized Dentin MatrixDental Implantsbone defectdemineralized dentin matrix particlesimmediate implantationsimple taper retention

Identifiers

PMID40899213
PMCPMC12419826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.