ReviewPhytotherapy research : PTR2026
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy.
Review in Phytotherapy research : PTR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy.Phytotherapy research : PTR · 2026Review
- Synthesis, Biological Evaluation and Structure-Activity Relationship of Juglone Derived Naphthoquinones as Potential Antipsoriatic Agents.Biomolecules · 2026Article
- Plant Extracts Downregulating the JAK/STAT Signaling Pathway as a Potential Tool for Psoriasis Management: A Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Psoriasis is a persistent inflammatory dermatological condition, predominantly influenced by genetic factors, immune system dysfunction, and environmental stimuli. It presents as red papules and silvery-white scales, resulting in physical discomfort and contributing to various comorbidities, including mental health disorders, arthritis, and cardiovascular complications, which collectively impose considerable medical and socioeconomic burdens. Conventional treatments, such as immunosuppressants and biologics, may alleviate symptoms but frequently entail significant side effects and the potential for dependency. This review evaluates the therapeutic potential of natural compounds, emphasizing their capacity to influence critical cellular pathways involved in the pathogenesis of psoriasis. Natural compounds exhibit anti-inflammatory, keratinocyte-regulating, and antioxidant properties, influencing mechanisms like the Th17/IL-17 axis and oxidative stress. The results indicate that natural compounds may function as an adjunctive treatment, providing a safer alternative to existing therapies by mitigating side effects and improving symptom management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.