Evidence map›Paper›PMID 40898959›Full record

ArticlePain management2025

Delayed adverse skin reaction to transcutaneous electrical nerve stimulation (TENS) electrodes.

Mark I Johnson

Abstract readCase Reports
In one paragraph

Article in Pain management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark I JohnsonCentre for Pain Research, School of Health, Leeds Beckett University, Leeds, UK.ORCID 0000-0002-9421-9622

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 76-year-old woman developed a delayed allergic reaction to adhesive pads following home use of transcutaneous electrical nerve stimulation (TENS) for pain management after a complex elbow dislocation. This case highlights the potential for delayed hypersensitivity reactions to TENS electrode pads. Although formal allergology testing was not performed, the woman's self-directed observations offered valuable insight. The clinical presentation and timing of symptom onset were more consistent with allergic rather than irritant contact dermatitis. Allergic contact dermatitis from TENS pads is often linked to specific allergens in the adhesive materials. Hypoallergenic alternatives aim to reduce this risk by eliminating or substituting known sensitizers. Interestingly, the reaction on the painful arm - where titanium plates had been surgically implanted - extended beyond the electrode placement, whereas on the unaffected, pain-free leg, it remained localized. This suggests that local tissue conditions may modulate the immune response. This case demonstrates the importance of clinician awareness regarding potential dermatological adverse events associated with TENS therapy and emphasizes the need for patient education, particularly when TENS is administered independently. Further investigation into the interaction between local inflammatory states and immune reactivity may inform safer electrode design and guide clinical recommendations for safe TENS use.

Indexed as

Dermatitis, Allergic ContactTranscutaneous Electric Nerve StimulationAgedElectrodesFemaleHumansAdverse eventAllergic reactionNeuromodulationPainTranscutaneous electrical nerve stimulation

Identifiers

PMID40898959
PMCPMC12691550

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.