ArticleACR open rheumatology2025
Falls Among Individuals With Systemic Lupus Erythematosus: An Observational Study.
Article in ACR open rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Prevalence of falls in a pooled US cohort of adults with systemic lupus erythematosus: a nested cross-sectional study.Lupus science & medicine · 2026Article
- Conditions identified by common comprehensive geriatric assessment measures and subsequent acute care among adults with SLE.Lupus science & medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveSystemic lupus erythematosus (SLE) is thought to accelerate the aging process. However, there is limited research on geriatric syndromes, such as falls, in this potentially vulnerable population. This study aimed to describe the prevalence of and contributors to falls in the SLE population.
methodsParticipants were recruited from an ongoing population-based cohort of individuals with validated SLE. Falls (number of falls and fall-related injuries requiring medical attention over the past year) and perceived contributing factors were self-reported. Descriptive statistics were calculated, and age-, sex-, and race-adjusted odds ratios (aORs) of participant characteristics with falls were estimated using multivariable logistic regression.
resultsNearly one-third (30.7%) of participants (overall N = 447; 40.9% aged ≥50 years, 91.7% female, and 82.6% Black) reported falling in the past year; 19.2% fell twice or more. Loss of balance (78.1% of falls), slipping/tripping (64.2%), and weakness (53.3%) were the most commonly reported contributing factors. Age and sex were not associated with falls, but higher physical performance (aOR, 0.78; 95% confidence interval [CI], 0.71-0.87) was associated with lower odds of falls. Higher SLE activity (aOR, 1.78; 95% CI, 1.44-2.21) and damage (aOR, 1.22; 95% CI, 1.00-1.49), greater depressive symptoms (aOR, 1.43; 95% CI, 1.14,1-80), and taking fall risk-increasing drugs (antidepressants: aOR, 1.82; 95% CI, 1.13-2.93; pain medications: aOR, 2.60; 95% CI, 1.68-4.00; opioids: aOR, 4.52; 95% CI, 2.39-8.56) were associated with higher odds of falls.
conclusionFalls were common in our cohort, regardless of age. Our results suggest potential interventions for reducing falls, like better control of SLE, physical therapy, depression screening, and medication review.
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Registered trials
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