ArticleMedicine2025
Application of tissue engineering in wound healing: A 20-year bibliometric and visualized study.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Current Status of Animal Models for Premature Ovarian Insufficiency: Similarities to Clinical Manifestations and Therapeutic Applications.Tissue engineering and regenerative medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundTissue engineering has recently been shown to have a considerable advantage in promoting wound healing in clinical studies and animal models, with an increasing number of documents in designing and mechanism investigations. The lack of bibliometric analysis and knowledge mapping in this field would hinder comprehensive understanding of this field and the development of future research.
methodsOur investigation into the application of tissue engineering in wound healing involved a search of the Web of Science Core Collection (WoSCC). To identify research hotspots and promising future trends in this field of study, we employed several software tools such as VOSviewer, CiteSpace, and R packages to evaluate the contribution and co-occurrence relationships across countries/regions, institutions, journals, authors, keywords, and references.
resultsUltimately, a total of 9820 documents were reviewed and analyzed. China emerged as the leading country in terms of productivity and influence in this particular field. Shanghai Jiao Tong University emerged as the top publisher, spearheading a group of prominent research institutions. Among journals, Biomaterials garnered the highest number of citations and co-citations, boasting impressive H-index, G-index, and M-index scores. Notably, Reis emerged as the most cited author, while Liu topped the list in terms of co-citations. Keyword and reference analyses unveiled 3 major research directions: natural endogenous technology involving multiple cells and functional factors, mechanism research on the practical application of tissue engineering technology in wound healing, and artificially synthesized and reprocessed exogenous technology. Among these, the latter represented the current focal point in the field.
conclusionThis research offered a comprehensive outlook on the present status and prospective direction of tissue engineering in wound healing applications worldwide. A thorough evaluation was conducted on diverse tissue engineering techniques, furnishing profound perspectives for scholars and serving as a credible resource that propelled advancements in the field while piquing the curiosity of researchers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.