Evidence map›Paper›PMID 40898348›Full record

ArticleWorld journal of emergency surgery : WJES2025

Health-related quality of life after emergency abdominal surgery.

Vladimir Sergeevich Gordeev, Esubalew Assefa, Rupert Pearse, Mark Edwards, Borislava Mihaylova

Abstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vladimir Sergeevich Gordeev *Health Economics and Policy Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, Yvonne Carter Building, 58 Turner Street, London, E1 2AB, UK.ORCID http://orcid.org/0000-0003-3906-2316
Esubalew Assefa *Health Economics and Policy Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, Yvonne Carter Building, 58 Turner Street, London, E1 2AB, UK.ORCID http://orcid.org/0000-0002-4850-6567
Rupert PearseFaculty of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-4373-5934
Mark EdwardsAnaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.ORCID http://orcid.org/0000-0002-5048-1784
Borislava MihaylovaHealth Economics and Policy Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, Yvonne Carter Building, 58 Turner Street, London, E1 2AB, UK. b.mihaylova@qmul.ac.uk.ORCID http://orcid.org/0000-0002-0951-1304

Funding

National Institute for Health and Care Research-Health and Social Care Delivery Research (HSDR) 12/5005/10National Institute for Health and Care Research: Health Technology Assessment 15/80/54
6 · The paper itself

Abstract

backgroundPatients' survival and quality of life are key factors in assessing value of treatments. However, limited evidence exists about the trajectory and key determinants of patients' health-related quality of life (QoL) following emergency abdominal surgery.

methodsUsing the Enhanced Peri-Operative Care for High-risk patients study with measured QoL during eight months follow-up using the EQ-5D-3L questionnaire, we summarise the trajectory of patients' QoL after emergency abdominal surgery and use multivariable regression models to relate patients' demographic and clinical characteristics, pre-surgery characteristics, and time elapsed since surgery with their QoL. In further analysis we assess the contribution of post-surgery patient characteristics.

resultsData from 686 patients undergoing emergency abdominal surgery (50.4% female; mean age 66.6 (standard deviation (SD) 12.8) years; 50.1% with intestinal obstruction as indication for surgery), with QoL measurements were analysed. Shortly after surgery (mean days 7.59 (SD 7.48)), the mean EQ-5D-3L QoL utility score was 0.21 (SD 0.46), which improved among survivors to 0.74 (SD 0.31) in the medium- to long-term (i.e., three to eight months) following surgery. Patient's sex and preoperative risk of mortality were key determinants of QoL shortly after surgery. In addition to time since surgery, patient's sex, Charlson Comorbidity index, ASA physical status and indication for surgery were key pre-surgery predictors of QoL in the medium- to long-term post-surgery. From post-surgery characteristics, duration of hospital admission for index surgery and further days in hospital within 30 days prior to QoL measurement were key further determinants of QoL in the medium- to long-term.

conclusionsIndividual patient, surgery, and recovery characteristics determine QoL post-emergency abdominal surgery and can help inform clinician-patient discussions and assessments of value of abdominal surgery interventions.

Indexed as

AbdomenQuality of LifeAgedFemaleHumansMaleMiddle AgedSurveys and QuestionnairesEmergency abdominal surgeryHealth-related quality of lifePost-surgery outcomesPrediction modellingSurgery

Identifiers

PMID40898348
PMCPMC12403461

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.