Evidence map›Paper›PMID 40898131›Full record

ArticleBMC surgery2025

Total knee arthroplasty for ankylosed knees in the extended position with hemophilia: a medium- and long-term single-center experience.

Zhongyi Zhang, Yi Tang, Zhaokai Jin, Lei Chen, Xinyu Hu, Yichen Gong, Shineng Lin, Guoqian Chen, Shuaijie Lv, Peijian Tong

Abstract read
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zhongyi Zhang *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Yi Tang *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Zhaokai JinThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Lei ChenThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Xinyu HuThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Yichen GongThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Shineng LinThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Guoqian ChenThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China.
Shuaijie Lv *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China. lvshuaijie1990@126.com.
Peijian TongThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian RoadZhejiang Province, Hangzhou, 310006, China. peijiantongzjtcm@163.com.

Funding

Project of Chunyan Special Fund for Chinese Medicine Development of Zhejiang Chinese Medical University No. CY202305the State Administration of Traditional Chinese Medicine of Zhejiang Province No.GZY-ZJ-KJ-23064the Zhejiang Provincial Natural Science Foundation of China No. LD22C060002
6 · The paper itself

Abstract

backgroundTotal knee arthroplasty (TKA) is one of the curative methods for patients with end-stage ankylosed knees. However, the existing methods are difficult to enable patients with hemophilic ankylosed knees to recover good functional activities.

methodsBetween January 2008 and December 2021, 22 male patients with ankylosed knees in the extended position due to hemophilia underwent TKA. The average age of the patients was 41.3 years (range, 19 to 52 years), and the average hospital stay was 33.4 days (range, 14 to 50 days). TKA was performed using quadriceps tendon Z-lengthening plasty, staged osteotomy, and comprehensive soft-tissue release. A variety of methods were used to evaluate the postoperative clinical outcomes and complications, including range of motion (ROM) assessment, Visual Analogue Scale (VAS), Knee Society Score (KSS), and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).

resultsAt the last follow-up, the average KSS increased from 75.14 ± 34.63 before surgery to 148.41 ± 27.74 (P < 0.001), the ROM increased from 0 to 86.14 ± 24.69 (P < 0.001), the WOMAC score changed from 28.05 ± 11.20 before surgery to 10.82 ± 11.00 (P < 0.001), and the average VAS score decreased from 2.86 ± 1.86 to 0.73 ± 1.20 (P < 0.001).

conclusionAlthough the recovery of range of motion is lower than normal and there is a relatively high incidence of complications, TKA can still significantly improve the flexion and extension functions, mobility, and quality of life of patients with ankylosed knees.

Indexed as

AnkylosisArthroplasty, Replacement, KneeHemophilia AKnee JointAdultFollow-Up StudiesHumansMaleMiddle AgedRange of Motion, ArticularRetrospective StudiesTreatment OutcomeYoung AdultAnkylosed KneeHemophiliaSingle-Center Medium- and Long-Term ExperienceSurgical TechniquesTotal Knee Arthroplasty

Identifiers

PMID40898131
PMCPMC12403424

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