ArticleBMC ophthalmology2025
Baseline ocular biometrics in children with orthokeratology-induced axial length reduction or elongation.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Establishing and validating a predictive model for long-term control outcomes following orthokeratology lenses wear: a five-year cohort study.Frontiers in cell and developmental biology · 2026Article
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Authors and funding
4 authors.
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Abstract
purposeTo determine the baseline ocular biometrics in children with axial length reduction after orthokeratology for better myopia control.
methodsChanges in ocular parameters in 164 subjects who completed one year of Ortho-K treatment were retrospectively reviewed. The subjects were divided into AL reduction (n = 105, ≤ 0 mm/year axial growth) and AL elongation (n = 59, ≥ 0.4 mm/year axial growth) groups based on 1-year axial length changes.
resultsCompared with those in the AL elongation group, children in the AL reduction group were older (p < 0.001), had a higher degree of myopia(p < 0.001), larger pupil diameter (p < 0.001), deeper anterior chamber depth (p = 0.007), and lower corneal endothelial density (p < 0.001). In the AL reduction group, the reduction was negatively correlated with WTW and CCT changes (ρ=-0.346, p < 0.001). Endothelial cell loss in the elongation group was 1.95 times greater than that in the reduction group (44.239 ± 79.629 vs.22.646 ± 79.038 cells/mm²).
conclusionsBaseline age, degree of myopia, pupil diameter, and anterior chamber depth were associated with the efficacy of orthokeratology in controlling axial length. The ΔWTW/ΔCCT ratio may be useful for predicting AL reduction. Regular examination of the corneal endothelium in children with rapid axial length elongation is recommended.
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