Evidence map›Paper›PMID 40898040›Full record

SynthesisBMC anesthesiology2025

The impact of perioperative hypothermia on surgical site infection risk: a meta-analysis.

Ruirong Chen, Yingjie Du, Lanyue Chen, Yafan Bai, Yue Zhang, Tiankuo Yu, He Li, Guyan Wang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruirong Chen *Department of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yingjie Du *Department of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Lanyue ChenDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yafan BaiDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Yue ZhangDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Tiankuo YuDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
He LiDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Guyan WangDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. guyanwang2006@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe connection between perioperative hypothermia and the occurrence of surgical site infections (SSIs) is still not clearly established. This investigation aimed to clarify the potential link between these two factors using meta-analytical techniques. MATERIALS AND

methodsThis investigation examined the potential connection of perioperative hypothermia to the risk of SSI. A comprehensive literature review was conducted utilizing PubMed, Web of Science, and Embase. The primary endpoint was the incidence of SSI. Pooled risk ratios were estimated using fixed- or random-effects meta-analysis. Sensitivity analyses were performed to evaluate the impact of preoperative hypothermia on the pooled risk of SSI. Statistical analyses were performed using Review Manager software and R software.

resultsOur meta-analysis encompassed 25 studies representing a total of 28,761 patients. The analysis revealed no statistically significant association between patients' intraoperative body temperature and their likelihood of developing post-surgical complications [odds ratio (OR), 1.39; 95% confidence interval (CI), 0.98-1.96; I

conclusionsThe findings suggest that the relationship between perioperative hypothermia and an increased incidence of SSI is not definitive; however, it is significantly associated with breast surgery and when body temperature falls below 35 °C. Future randomized controlled trials (RCTs) should focus on breast surgery and standardize temperature thresholds. Due to the high heterogeneity, the interpretation of this result should be approached with caution, and there is a call for future high-quality research.

Indexed as

HypothermiaIntraoperative ComplicationsSurgical Wound InfectionHumansRisk FactorsMeta-analysisPerioperative hypothermiaSSI

Identifiers

PMID40898040
PMCPMC12403262

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.