ArticleBMC plant biology2025
Genome-wide identification and characterization of DUF789 genes in cotton: implications for fibre development.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- TheInternational journal of molecular sciences · 2026Article
- The KeyPlants (Basel, Switzerland) · 2026Article
- Characterization, evolution, and expression profiling of cotton DUF677 protein family and their potential role in drought and salt stress response.BMC plant biology · 2026Article
- Comprehensive analysis of TGA genes in barley: structure, evolution, and stress-responsive expression.BMC plant biology · 2026Article
- Transcriptional and post-transcriptional regulatory networks controlling cotton fibre development.Plant molecular biology · 2026Review
- Genome-wide identification and functional characterisation of the EDS1 gene family reveals evolutionary conservation and stress-responsive regulatory roles in barley.Scientific reports · 2026Article
- Genome-Wide Identification of Histone Acetyltransferases inJournal of fungi (Basel, Switzerland) · 2026Article
- Genome-wide identification and comparative analysis ofFrontiers in plant science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProteins containing domains of unknown function (DUFs) play a crucial role in plant growth, development and stress adaptation, but many of them are still uncharacterized. The DUF789 family is one of the least studied of these, especially in economically significant crops like cotton (Gossypium spp.), whose possible function in fibre production and abiotic stress response is yet unknown.
resultsIn a comprehensive genome-wide analysis, a total of 91 DUF789 genes were identified in four Gossypium species: G. arboreum, G. barbadense, G. raimondii and G. hirsutum. Evolutionary and phylogenetic analyses placed the GhDUF789 proteins into different clades, with purifying selection identified as the major evolutionary force. Analyses of gene structure and conserved motifs revealed considerable structural diversity, with closely related genes showing similar exon-intron patterns and motif compositions. Synteny and duplication analyses showed that segmental and tandem duplications contributed to the DUF789 family expansion in cotton. Analysis of cis-regulatory elements revealed that the GhDUF789 promoters are enriched in motifs responsive to hormonal, developmental, light-induced and abiotic stresses. GO enrichment analyses, prediction of protein-protein interaction and secondary and tertiary structure modelling, indicated that GhDUF789 proteins are involved in clathrin-mediated vesicle trafficking and membrane trafficking. The miRNA target prediction revealed regulatory interactions with conserved miRNAs from cotton, in particular ghr-miR414 and ghr-miR396. Expression profiling based on transcriptome analysis, supported by validation using qRT-PCR, revealed that several GhDUF789 genes are differentially expressed during fibre development and respond strongly to drought, heat, salinity and cold stress, especially in drought-tolerant genotypes.
conclusionsThis study provides the first comprehensive characterization of the DUF789 gene family in cotton and offers new insights into its evolutionary dynamics, structural features and potential role in fibre development and adaptation to abiotic stress. The results provide a solid foundation for future functional studies and identify candidate GhDUF789 genes for targeted genetic improvement of stress resistance and fibre quality in cotton.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.