Evidence map›Paper›PMID 40897665›Full record

ArticleInvestigative and clinical urology2025

Influence of bladder outlet obstruction on age-related changes in male bladder contractility.

Jin Bong Choi, Kang Jun Cho, Joon Chul Kim, Young Kyu Han, Ju Hun Ahn, Seong Joo Yang, Jun Sung Koh

Abstract read
In one paragraph

Article in Investigative and clinical urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. PIEZO1-mediated mechanosensation links aging to bladder dysfunction.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin Bong ChoiDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0000-0003-2508-6819
Kang Jun ChoDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0000-0002-5305-901X
Joon Chul KimDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0000-0002-4019-620X
Young Kyu HanDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0009-0002-4041-7321
Ju Hun AhnDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0009-0003-6296-7364
Seong Joo YangDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0009-0004-6792-5013
Jun Sung KohDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. gostraight@catholic.ac.kr.ORCID 0000-0001-7432-4209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChanges in bladder contractility due to aging are among the important causes of lower urinary tract symptoms (LUTS) in elderly males. The purpose of this study was to observe changes in bladder contractility due to aging in male patients taking medications commonly used to treat LUTS in clinical practice. MATERIALS AND

methodsMale patients aged over 40 years who underwent urodynamic studies for LUTS from January 2012 to December 2024 were included. The bladder outlet obstruction (BOO) index was used to distinguish between males with BOO and those without BOO. Changes in bladder contractility according to age in each group were analyzed using the bladder contractility index. The Pearson correlation coefficient (

resultsA total of 449 male patients who underwent urodynamic studies for LUTS were eligible for this study (311 in the BOO group and 138 in the BOO group). Age and the maximum flow rate were inversely related in both groups. Age and bladder contractility were significantly correlated in the non-BOO group (p=0.021) but not in the BOO group (p=0.057).

conclusionsThis study revealed that BOO might act as a confounding variable in measuring the contractility of an aged bladder. Excluding the effect of BOO, bladder contractility significantly decreases with age. Therefore, when male LUTS are treated, changes in bladder contractility due to aging vary depending on BOO.

Indexed as

AgingLower Urinary Tract SymptomsMuscle ContractionUrinary BladderUrinary Bladder Neck ObstructionAdultAgedAged, 80 and overAge FactorsHumansMaleMiddle AgedRetrospective StudiesUrodynamicsAgingBladderBladder outlet obstructionLower urinary tract symptoms

Identifiers

PMID40897665
PMCPMC12437572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.