Evidence map›Paper›PMID 40897484›Full record

ArticleBMJ open2025

Study protocol: neonatal colonisation and infection with

Kirsten Glaser, Judith Rittenschober-Böhm, Alexander Humberg, Guido Stichtenoth, Sarina Butzer, Katrin Mehler, Florian Kipfmüller, Natascha Köstlin-Gille, Christian Gille, Andrea Kick and 5 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kirsten GlaserDivision of Neonatology, Department of Women's and Children's Health, University of Leipzig Medical Center, Leipzig, Germany.ORCID http://orcid.org/0000-0002-2158-0222
Judith Rittenschober-BöhmDivision of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics and Adolescent Medicine, Comprehensive Centre for Pediatrics, Medical University of Vienna, Vienna, Austria.
Alexander HumbergDepartment of Pediatrics, University Hospital Münster, Münster, Germany.
Guido StichtenothDepartment of Pediatrics, University Hospital of Lübeck, Lübeck, Germany.
Sarina ButzerUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Division of Pediatric Infectious Diseases, Köln, Germany.
Katrin MehlerUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Division of Pediatric Infectious Diseases, Köln, Germany.
Florian KipfmüllerDepartment of Neonatology and Pediatric Intensive Care Medicine, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Natascha Köstlin-GilleDepartment of Neonatology, Tübingen University Children's Hospital, Tübingen, Germany.
Christian GilleDepartment of Neonatology, Heidelberg University, Medical Faculty, Heidelberg, Germany.
Andrea KickKlinik Hallerwiese-Cnopf'sche Kinderklinik, Clinic for Neonatology and Paediatric Intensive Care, Nürnberg, Germany.
Diana DornisDivision of Neonatology, Department of Women's and Children's Health, University of Leipzig Medical Center, Leipzig, Germany.
Birgit HenrichInstitute of Medical Microbiology and Hospital Hygiene, University Clinic of Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Alex FarrDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, and Comprehensive Center for Pediatrics (CCP), Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-4628-9052
Christoph HärtelUniversity Hospital Würzburg, University of Würzburg, Department of Pediatrics, Würzburg, Germany.
Christine SilwedelUniversity Hospital Würzburg, University of Würzburg, Department of Pediatrics, Würzburg, Germany silwedel_c@ukw.de.ORCID http://orcid.org/0000-0002-9678-326X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreterm infants, particularly those born before 29 weeks of gestation, are at increased risk of developing bronchopulmonary dysplasia (BPD) and other complications of prematurity. Substantial evidence suggests that respiratory tract colonisation with METHODS AND ANALYSIS: This is a prospective observational multicentre study being conducted in level III neonatal intensive care units in Germany and Austria. In total, 400 infants born before 29 weeks of gestation are screened for ETHICS AND DISSEMINATION: The study has been approved by the ethics committees in Würzburg and Leipzig and the local ethics committees of all participating centres. Results will be disseminated through peer-reviewed international publications and conferences. The study is registered with the German Clinical Trials Register, ID DRKS00033001. TRIAL REGISTRATION NUMBER: German Clinical Trials Register (DRKS00033001).

Indexed as

Bronchopulmonary DysplasiaInfant, Premature, DiseasesUreaplasmaUreaplasma InfectionsFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleMulticenter Studies as TopicObservational Studies as TopicProspective StudiesInflammationMICROBIOLOGYNEONATOLOGYPAEDIATRICSPulmonary Disease

Identifiers

PMID40897484
PMCPMC12406933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.