Evidence map›Paper›PMID 40897110›Full record

ArticleInternational journal of hygiene and environmental health2025

Household air pollution exposure in adult women is associated with increased carotid intima-media thickness: A cross-sectional study of the Household Air Pollution Intervention Network trial.

Lindsay J Underhill, Lisa de Las Fuentes, Laura Nicolaou, Shakir Hossen, Anaite Diaz-Artiga, Ajay Pillarisetti, Aris T Papageorghiou, Florien Ndagijimana, Ghislaine Rosa, Gurusamy Thangavel and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of hygiene and environmental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Lindsay J UnderhillCardiovascular Division and Global Health Center, Washington University School of Medicine, St. Louis, MO, USA.
Lisa de Las FuentesCardiovascular Division and Global Health Center, Washington University School of Medicine, St. Louis, MO, USA; Center for Biostatistics and Data Science, Institute for Informatics, Data Science, and Biostatistics (I2BD), Washington University School of Medicine, St. Louis, MO, USA.
Laura NicolaouDivision of Pulmonary and Critical Care, School of Medicine and Center for Global Non-Communicable Disease Research and Training, Johns Hopkins University, Baltimore, MD, USA.
Shakir HossenDepartment of Preventive Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Anaite Diaz-ArtigaCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Ajay PillarisettiDivision of Environmental Health Sciences, University of California at Berkeley, Berkeley, California, USA.
Aris T PapageorghiouNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Florien NdagijimanaEagle Research Centre, Kigali, Rwanda.
Ghislaine RosaDepartment of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Gurusamy ThangavelDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
John P McCrackenDepartment of Environmental Health Sciences, University of Georgia, Athens, GA, USA.
Kalpana BalakrishnanDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
Krishnendu MukhopadhyayDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
Kyle SteenlandGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Lisa M ThompsonGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA; Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Lance A WallerDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Maggie L ClarkDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Michael A JohnsonBerkeley Air Monitoring Group, Berkeley, CA, USA.
Sarada GargDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
Sankar SambandamDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
Suzanne M SimkovichDivision of Healthcare Delivery Research, MedStar Health Research Institute, Hyattsville, MD, USA; Division of Pulmonary and Critical Care Medicine, Georgetown University, Washington, DC, USA.
Vigneswari AravindalochananDepartment of Environmental Health Engineering, Sri Ramachandra Institute for Higher Education and Research, Chennai, India.
Kendra N WilliamsDivision of Pulmonary and Critical Care, School of Medicine and Center for Global Non-Communicable Disease Research and Training, Johns Hopkins University, Baltimore, MD, USA.
Wenlu YeWorld Health Organization, Geneva, Switzerland.
Jennifer L PeelDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Thomas F ClasenGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine and Center for Global Non-Communicable Disease Research and Training, Johns Hopkins University, Baltimore, MD, USA.
Victor G Davila-RomanCardiovascular Division and Global Health Center, Washington University School of Medicine, St. Louis, MO, USA; Global Health Innovation Network, WashU School of Public Health, St. Louis, MO, USA. Electronic address: vdavila@wustl.edu.
HAPIN Investigators

Funding

Household Air Pollution and Health: A Multi-Country LPG Intervention TrialUM1HL134590 · NHLBI · EMORY UNIVERSITY · PI CHECKLEY, WILLIAM, CLASEN, THOMAS F · 2016 to 2021
$31.1M
NHLBI NIH HHS UM1 HL134590World Health Organization 001
6 · The paper itself

Abstract

backgroundCardiovascular disease is the leading cause of global morbidity and mortality, disproportionately affecting people in low- and middle-income countries (LMICs). Biomass fuels used for cooking in LMICs contribute significantly to household air pollution (HAP), which has been associated with inflammation, oxidative stress, and other pathways linked to atherosclerosis. We evaluate the association between HAP exposure and atherosclerosis by use of carotid artery ultrasound.

methodsAn exposure-response analysis was conducted using cross-sectional baseline data from 397 women aged 40-79 years from the Household Air Pollution Intervention Network (HAPIN) trial in Guatemala, India, Peru, and Rwanda. Participants underwent ultrasound evaluation of their carotid arteries to measure intima-media thickness (CIMT) and atherosclerotic plaques. Additionally, 24-h personal exposures to particulate matter (PM

findingsMean 24-h PM

interpretationIn this cross-sectional study, higher personal exposures to PM

Indexed as

Air PollutantsAir Pollution, IndoorAtherosclerosisCarotid Intima-Media ThicknessEnvironmental ExposureAdultAgedCarbon MonoxideCookingCross-Sectional StudiesFemaleHumansIndiaMiddle AgedParticulate MatterPeruAir PollutantsCarbon MonoxideParticulate MatterSootAtherosclerosisCarotid artery ultrasoundHousehold air pollution

Identifiers

PMID40897110
PMCPMC13295014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.