Evidence map›Paper›PMID 40897017›Full record

ArticleEnvironment international2025

Lifetime air pollution exposure from prenatal to 18 years and cardiovascular health in young adulthood: findings from a UK birth cohort.

Ana Goncalves Soares, Kate Tilling, Maryam Makanvand, Jules Kerckhoffs, Anna L Hansell, Nicholas J Timpson, Ahmed Elhakeem

Abstract read
In one paragraph

Article in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Goncalves SoaresMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. Electronic address: analuiza.soares@bristol.ac.uk.
Kate TillingMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Maryam MakanvandMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Jules KerckhoffsInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
Anna L HansellCentre for Environmental Health and Sustainability, University of Leicester, Leicester, UK; NIHR Health Protection Research Unit in Environmental Exposures and Health at the University of Leicester, UK.
Nicholas J TimpsonMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Ahmed ElhakeemMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Funding

Department of Health NIHR200901Medical Research Council MC_UU_00011/6Wellcome Trust 217065
6 · The paper itself

Abstract

aimsWe assessed the association between air pollution from pregnancy (in utero) to 18 years and cardiovascular health markers in early adulthood.

methodsData from 3,767 individuals from a UK birth cohort were used. We explored the associations between modelled fine particulate matter (PM

resultsHigher average levels of PM

conclusionsHigher lifetime exposure to air pollution up to 18 years was associated with markers of poorer cardiovascular health in early adulthood.

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesEnvironmental ExposurePrenatal Exposure Delayed EffectsAdolescentBirth CohortBlood PressureCohort StudiesFemaleHumansMaleNitrogen DioxideParticulate MatterPregnancySootAir PollutantsNitrogen DioxideParticulate MatterSootALSPACCardiovascular healthLifetime air pollutionLong-term air pollutionYoung adulthood

Identifiers

PMID40897017
PMCPMC7618702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.