ArticleFrontiers in surgery2025
Development and validation of a nomogram for predicting postoperative intraluminal hemorrhage in patients undergoing laparoscopic pancreaticoduodenectomy.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aims to investigate the risk factors for postoperative intraluminal hemorrhage (IPPH) after laparoscopic pancreaticoduodenectomy (LPD), with the aim of enhancing clinical management through the exploration and development of a risk prediction model with those factors. Method: The clinical data of 326 hospitalized patients between January 2020 and August 2023 who underwent LPD for malignancies were retrospectively selected. The data consisted of general conditions, comorbidities, preoperative treatments, laboratory tests, and postoperative complications. We explored the risk factors associated with postoperative intraluminal hemorrhage using univariate and multivariate logistic regression analyses and developed a predictive model of IPPH after LPD. Results: The incidence of IPPH in LPD patients was 7.06%. Advanced age (OR = 1.065, 95% CI = 1.001-1.133, Conclusion: Risk factors for IPPH include advanced age, low fibrinogen levels, low albumin levels, CR POPF, and IAI. These risk factors were used to develop a nomogram for identifying patients at high risk of IPPH, allowing for targeted interventions to address modifiable risk factors promptly and improve patient outcomes.
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