Evidence map›Paper›PMID 40896735›Full record

ArticleFrontiers in neuroinformatics2025

The BrainHealth Databank: a systems approach to data-driven mental health care and research.

Jose Arturo Santisteban, David Rotenberg, Stefan Kloiber, Marta M Maslej, Adeel Ansari, Bahar Amani, Darren Courtney, Farhat Farrokhi, Natalie Freeman, Masooma Hassan and 14 more

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jose Arturo SantistebanKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
David RotenbergKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Stefan KloiberCentre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Toronto, ON, Canada.
Marta M MaslejKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Adeel AnsariKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Bahar AmaniCundill Centre for Child and Youth Depression, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Darren CourtneyDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Farhat FarrokhiData and Insights, Information Management Group, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Natalie FreemanCentre for Addiction and Mental Health, Toronto, ON, Canada.
Masooma HassanCentre for Addiction and Mental Health, Toronto, ON, Canada.
Lucia KwanCentre for Addiction and Mental Health, Toronto, ON, Canada.
Mindaugas MozuraitisData and Insights, Information Management Group, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Michael LauKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Natalia PotapovaKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Farhad QureshiKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Nicole SchoerKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Nelson ShenKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Joanna YuKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Noelle CoombeCentre for Addiction and Mental Health, Toronto, ON, Canada.
Kimberly HunterCentre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Toronto, ON, Canada.
Peter SelbyCentre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Toronto, ON, Canada.
Nicole ThomsonInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Damian JankowiczCentre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, Toronto, ON, Canada.
Sean L HillKrembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mental health care is undermined by fragmented data collection, as incomplete datasets can compromise treatment efficacy and research. The BrainHealth Databank (BHDB) at the Centre for Addiction and Mental Health (CAMH) establishes the governance and infrastructure for a Learning Mental Health System that integrates digital tools, measurement-based care, artificial intelligence (AI), and open science to deliver personalized, data-driven care. Methods: Central to the BHDB's approach is its comprehensive governance framework, which actively engages clinicians, researchers, data scientists, privacy and ethics experts, and patient and family partners. This codesigned approach ensures that digital health technologies are deployed ethically, securely, and effectively within clinical settings. Results: By aligning data collection with clinical and research goals and harmonizing over 12 million data points from 33,000 patient trajectories, the BHDB enhances data quality, enables real-time decision support, and fosters continuous improvement. Discussion: The BHDB provides a model for integrating AI and digital tools into mental health care, as well as research data collection, analyses, storage, and sharing through the BHDB Portal (https://bhdb.camh.ca).

Indexed as

AIdatadigitizationlearning health systemmental healthOpen Sciencesystem approach

Identifiers

PMID40896735
PMCPMC12392782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.