Evidence map›Paper›PMID 40896494›Full record

ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025

Methionine metabolism, functions, and application in swine.

Mengliao Wan, Yulong Yin, Yehui Duan, Jiashun Chen

Abstract readReview
In one paragraph

Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chemotyping ofPlants (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mengliao WanHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
Yulong YinHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
Yehui DuanHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
Jiashun ChenCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methionine (Met) is the only sulfur-containing essential amino acid for animals and is the second or third limiting amino acid in swine diets. It plays a role not only in protein synthesis, but also as an important methyl donor to participate in various biochemical reactions. Additionally, Met can be converted into several functional derivatives, such as S-adenosylmethionine (SAM) and homocysteine (Hcy) through which it exerts its biological functions. Specifically, appropriate supplementation with Met or SAM has been shown to provide a wide range of health-promoting effects, particularly in enhancing reproductive performance, improving intestinal morphology, regulating hepatic lipid metabolism, promoting muscle growth, and improving meat quality. In contrast, elevated Hcy levels can increase oxidative stress and inflammation, negatively affecting reproductive performance. Supplemental Met has been widely used in swine production for many years. This review summarizes recent advances in the application of Met and its derivatives in the pig industry, and explores their mechanism of action and optimal dosage as a feed additive, aiming to support the effective development and rational use of Met.

Indexed as

MethionineMethionine applicationMethionine metaboliteSwine

Identifiers

PMID40896494
PMCPMC12395089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.