Evidence map›Paper›PMID 40896444›Full record

ReviewFrontiers in oncology2025

Open partial or transoral laryngectomy - total laryngectomy today.

Dietmar Thurnher, Ricard Simo, Giovanni Succo, Isabel Vilaseca, Christian Simon

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dietmar ThurnherDepartment of Otorhinolaryngology, Medical University of Graz, Graz, Austria.
Ricard SimoDepartment of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Giovanni SuccoENT Clinic - Head and Neck Cancer Unit, San Giovanni Bosco Hospital, Turin, Italy.
Isabel VilasecaOtolaryngology and Head and Neck Surgery Unit, Hospital Clinic, Barcelona, Spain.
Christian SimonDepartment of Otolaryngology-Head and Neck Surgery, CHUV, University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total laryngectomy, a surgical procedure involving the complete removal of the larynx, has been a crucial treatment for advanced laryngeal cancer since its introduction in 1873. Over the past 150 years, this procedure has evolved significantly, with improvements in surgical techniques, postoperative care, and rehabilitation methods leading to better survival rates and quality of life for patients. While organ-preserving approaches like radiochemotherapy have gained prominence in recent decades, total laryngectomy remains an essential option for cases of advanced cancer or when other treatments fail. This review explores the history, development, and current role of total laryngectomy in treating laryngeal cancer, as well as comparing it to alternative surgical approaches like open partial laryngectomy and transoral laser microsurgery or organ preservation protocols.

Indexed as

organ preservationpartial horizontal laryngectomytotal laryngectomytransoral laser surgeryvoice rehabilitation

Identifiers

PMID40896444
PMCPMC12394142

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.