Evidence map›Paper›PMID 40896434›Full record

ArticleFrontiers in oncology2025

Yingao Zhang, Savannah Barkdull, Panayiotis D Kontoyiannis, Alejandra Flores Legarreta, David M Gershenson, Preetha Ramalingam, Michael M Frumovitz, Anil K Sood

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingao ZhangDepartment of Obstetrics & Gynecology, Baylor College of Medicine, Houston, TX, United States.
Savannah BarkdullDepartment of Obstetrics & Gynecology, Baylor College of Medicine, Houston, TX, United States.
Panayiotis D KontoyiannisMcGovern Medical School, University of Texas Health Science Center, Houston, TX, United States.
Alejandra Flores LegarretaDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas Medical Doctor (MD) Anderson Cancer Center, Houston, TX, United States.
David M GershensonDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas Medical Doctor (MD) Anderson Cancer Center, Houston, TX, United States.
Preetha RamalingamDepartment of Anatomical Pathology, University of Texas Medical Doctor (MD) Anderson Cancer Center, Houston, TX, United States.
Michael M FrumovitzDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas Medical Doctor (MD) Anderson Cancer Center, Houston, TX, United States.
Anil K SoodDepartment of Gynecologic Oncology and Reproductive Medicine, University of Texas Medical Doctor (MD) Anderson Cancer Center, Houston, TX, United States.

Funding

Harnessing the power of exosomes for non-coding RNA deliveryR35CA209904 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SOOD, ANIL K · 2017 to 2023
$5.0M
NCI NIH HHS R35 CA209904
6 · The paper itself

Abstract

Objective: Mucinous ovarian carcinomas (mOC) often harbor unique molecular alterations differentiating them from other epithelial ovarian carcinoma subtypes. We sought to characterize the somatic genomic mutation patterns in mOC and elucidate their associations with oncologic outcomes. Methods: All patients with mOC treated at a single institution between 2005-2023 were identified, and those with validated tumor molecular profiling (TMP) using next-generation sequencing of somatic variants were included. Progression-free survival (PFS) and overall survival (OS) were calculated on a Kaplan-Meier estimator. Multivariable analysis was performed using Cox regression models. Results: Forty patients were included in this retrospective cohort; 34 (85%) had at least 1 genomic alteration on TMP, with a median of 3 mutations (range 0-30). Conclusion: A substantial proportion of mOCs have concurrent

Indexed as

genomic sequencingmolecular sequencingmucinous adenocarcinomaNGSovarian cancerTP53tumor mutation

Identifiers

PMID40896434
PMCPMC12390820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.