Evidence map›Paper›PMID 40896387›Full record

ArticleJournal of scleroderma and related disorders2025

A rare case of scleredema associated with breast cancer.

Jenifer Centeno Gavica, Rupak Thapa

Abstract readCase Reports
In one paragraph

Article in Journal of scleroderma and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jenifer Centeno GavicaDepartment of Rheumatology, Atrium Health Wake Forest Baptist, Winston Salem, NC, USA.ORCID https://orcid.org/0009-0001-6664-1666
Rupak ThapaDepartment of Rheumatology, Atrium Health Wake Forest Baptist, Winston Salem, NC, USA.ORCID https://orcid.org/0009-0001-5232-0300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SclerEDEMA is a rare condition marked by diffuse skin thickening, often confused with sclerODERMA. It is linked with infections, malignancies, and diabetes. Although scleredema is associated with hematologic malignancies like multiple myeloma, it has not been reported with breast cancer, as suspected in this patient. We present a case of a patient diagnosed with scleredema, confirmed through skin biopsy. Subsequent cancer screenings identified a 6 mm breast nodule, which was confirmed as grade 3 ductal carcinoma. This newfound association between scleredema and breast cancer highlights the importance of vigilant health maintenance and regular cancer screenings in these patients.

Indexed as

breast cancercancer screeninghealth maintenanceScleredemascleroderma

Identifiers

PMID40896387
PMCPMC12398460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.