Evidence map›Paper›PMID 40896370›Full record

ArticleMachine learning in medical imaging. MLMI (Workshop)2025

Pseudo-Rendering for Resolution and Topology-Invariant Cortical Parcellation.

Pablo Blasco Fernandez, Karthik Gopinath, John Williams-Ramirez, Rogeny Herisse, Lucas J Deden-Binder, Dina Zemlyanker, Theressa Connors, Liana Kozanno, Derek Oakley, Bradley Hyman and 2 more

Abstract read
In one paragraph

Article in Machine learning in medical imaging. MLMI (Workshop), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pablo Blasco FernandezETH Zurich, Zurich, Switzerland.
Karthik GopinathMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
John Williams-RamirezMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
Rogeny HerisseMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
Lucas J Deden-BinderMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
Dina ZemlyankerMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
Theressa ConnorsMassachusetts Alzheimer Disease Research Center, Massachusetts General Hospital & Harvard Medical School.
Liana KozannoDepartment of Pathology, Massachusetts General Hospital.
Derek OakleyDepartment of Pathology, Massachusetts General Hospital.
Bradley HymanDepartment of Neurology, Massachusetts General Hospital.
Sean I YoungMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.
Juan Eugenio IglesiasMartinos Center for Biomedical Imaging, MGH & Harvard Medical School.

Funding

Functionally guided adult whole brain cell atlas in human and NHPUM1MH130981 · NIMH · ALLEN INSTITUTE · PI Ed Lein, Hongkui Zeng · 2022 to 2026
$91.9M
Acquisition-independent machine learning for morphometric analysis of underrepresented aging populations with clinical and low-field brain MRIRF1AG080371 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Juan Eugenio Iglesias Gonzalez · 2023 to 2026
$4.0M
Diagnosing the undiagnosable: studies of Alzheimer disease mimics and confounders via "neuropathometry" of dissection photos with 3D scanningR01AG070988 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI IGLESIAS GONZALEZ, JUAN EUGENIO · 2021 to 2025
$2.7M
Open-source software for multi-scale mapping of the human brainRF1MH123195 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE, IGLESIAS GONZALEZ, JUAN EUGENIO · 2020 to 2020
$2.0M
NIA NIH HHS R01 AG070988NIA NIH HHS RF1 AG080371NIMH NIH HHS RF1 MH123195NIMH NIH HHS UM1 MH130981
6 · The paper itself

Abstract

Parcellation of mesh models for cortical analysis is a central problem in neuroimaging. Most classical and deep learning methods have requisites in terms of mesh topology, requiring inputs that are homeomorphic to a sphere (i.e., no holes or handles). Topology correction algorithms do exist, but their computational complexity is quadratic with the size of the topological defects - sometimes hours, effectively precluding segmentation of incorrect meshes, including those derived from imperfect segmentations or obtained from inherently noisy modalities like surface scanning. Furthermore, deep learning mesh segmentation also struggles surface scans of brains because they are relatively nondescript and require modeling of longer-range dependencies. Here we propose "pseudo-render-inverse-render" (PRIR), a novel perspective on cortical mesh parcellation that effectively reframes the problem as a 2D segmentation task using an direct-inverse rendering framework. Our approach:

Identifiers

PMID40896370
PMCPMC12398396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.