Evidence map›Paper›PMID 40896254›Full record

ArticlemicroPublication biology2025

Apoptosis and Brain Dervived Neurotrophic Factor are increased in cortical neurons of Marfan Syndrome mice.

Mitra Esfandiarei, Faizan Anwar, Manogna Nuthi, Alisha Harrison, Mary Eunice Barrameda, Tala Curry-Koski, Kasey Pull, Theresa Currier Thomas, Nafisa Jadavji

Abstract read
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mitra EsfandiareiBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Faizan AnwarBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Manogna NuthiBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Alisha HarrisonBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Mary Eunice BarramedaBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Tala Curry-KoskiChild Health, University of Arizona, Tucson, Arizona, United States.
Kasey PullBiomedical Sciences, Midwestern University, Downers Grove, Illinois, United States.
Theresa Currier ThomasChild Health, University of Arizona, Tucson, Arizona, United States.
Nafisa JadavjiBiomedical Sciences, Southern Illinois University Carbondale, Carbondale, Illinois, United States.

Funding

TARGETING ENDOTHELIAL DYSFUNCTION IN A GENETIC MOUSE MODEL OF AORTIC ANEURYSM: IMPLICATIONS FOR PREVENTION AND THERAPYR15HL145646 · NHLBI · MIDWESTERN UNIVERSITY · PI ESFANDIAREI, MITRA · 2019 to 2019
$441k
NHLBI NIH HHS R15 HL145646
6 · The paper itself

Abstract

Marfan Syndrome (MFS) is an autosomal dominant genetic disorder that affects connective tissue throughout the body due to mutations in the fibrillin-1 (

Identifiers

PMID40896254
PMCPMC12391915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.