Evidence map›Paper›PMID 40896218›Full record

ArticleFrontiers in psychiatry2025

Suicidal risk and psychopathological profiles in adolescents with neurodevelopmental disorders: an Italian multicentric study.

Ramona Cardillo, Irene Di Modica, Francesca Cucinotta, Federica Galletta, Alessia Raffagnato, Marcella Di Cara, Carmela De Domenico, Eva Germanò, Sara Carucci, Giuseppe Abbracciavento and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Ramona Cardillo *Department of Developmental Psychology and Socialization, University of Padua, Padua, Italy.
Irene Di Modica *Child and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Francesca CucinottaIstituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi Bonino Pulejo, Department of Bioparco delle intelligenze e delle neurofragilità, Messina, Italy.
Federica GallettaChild and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Alessia RaffagnatoChild and Adolescent Neuropsychiatry Unit, Department of Women's and Children's Health, Padua University Hospital, Padua, Italy.
Marcella Di CaraIstituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi Bonino Pulejo, Department of Bioparco delle intelligenze e delle neurofragilità, Messina, Italy.
Carmela De DomenicoIstituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi Bonino Pulejo, Department of Bioparco delle intelligenze e delle neurofragilità, Messina, Italy.
Eva GermanòChild and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Sara CarucciChild and Adolescent Neuropsychiatry Unit, Department of Medical Sciences and Public Health, University of Cagliari and "A Cao" Pediatric Hospital, Cagliari, Italy.
Giuseppe AbbracciaventoChild and Adolescent Neuropsychiatry Unit, Department of Medical Sciences and Public Health, University of Cagliari and "A Cao" Pediatric Hospital, Cagliari, Italy.
Rita MurtasChild and Adolescent Neuropsychiatry Unit, Department of Medical Sciences and Public Health, University of Cagliari and "A Cao" Pediatric Hospital, Cagliari, Italy.
Alessia DoniaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Giuliana BonelliChild and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Serenella GrittaniDepartment of Mental Health, Center for Children with Autism Spectrum Disorder (ASD), Rimini, Italy.
Evamaria LanzariniChild and Adolescent Neuropsychiatry Unit, Infermi Hospital, Rimini, Italy.
Arianna AccettaChild and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Martina PirroneChild and Adolescent Neuropsychiatry Unit, Department of Human and Evolutionary Pathology "Gaetano Barresi", University of Messina, Messina, Italy.
Carola CostanzaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, Palermo, Italy.
Rosamaria SiracusanoDivision of Child Neurology and Psychiatry, University Hospital Federico II, Napoli, Italy.
Clemente CedroDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
Michela GattaChild and Adolescent Neuropsychiatry Unit, Department of Women's and Children's Health, Padua University Hospital, Padua, Italy.
Antonella GaglianoChild and Adolescent Neuropsychiatry, Department of Medicine and Surgery, "Kore" 90 University of Enna, Enna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Suicidal spectrum behaviors (SSB) consist of a continuum ranging from non suicidal self-injury, suicidal ideation, and suicide attempt to committed suicide. In adolescence, suicide is currently the second cause of death among adolescents aged 15 to 24 years and the third leading cause in children aged 10 to 14 years. Adolescents with Neurodevelopmental Disorders (NDDs), especially those with Autism Spectrum Disorder and Attention Deficit/Hyperactivity Disorder, are at heightened risk. Methods: This is a cross-sectional, multicenter research study, which involves four Italian child neuropsychiatry units (Messina, Padua, Rimini, and Cagliari). The study aims to define a specific neuropsychological and psychopathological profile associated with suicidal behaviors in adolescents and pre-adolescents with NDDs (11-18 years). In a sample of 127 NDDs adolescents (60 females and 67 males), with and without SSB, several variables were compared through standardized measures, including emotional dysregulation, impulsivity, and irritability as well as environmental risk factors. Results: The results of this study are consistent with the literature data and suggest that emotional dysregulation (p <.001) as an individual factor and Adverse Childhood Experiences (p = .002), as environmental factors, play a key role in promoting suicidality in pre-adolescents and adolescents with NDDs. Discussion: This awareness prompts the implementation of useful prevention methods during the clinical follow-up of individuals with NDDs.

Indexed as

adolescentsadverse life eventsemotional dysregulationneurodevelopmental disorderspre-adolescentssuicidal spectrum behaviors

Identifiers

PMID40896218
PMCPMC12394981

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