Evidence map›Paper›PMID 40896112›Full record

ArticleAdvanced materials technologies2025

Recent Advances in Handheld and Robotic Bioprinting Approach for Tissue Engineering.

Meenakshi Kamaraj, Nafiseh Moghimi, Akshat Joshi, Omid Rezayof, Alison Barer, Selena Cao, Rachael Orkin, Farshid Alambeigi, Johnson V John

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials technologies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meenakshi KamarajTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Nafiseh MoghimiTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Akshat JoshiTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Omid RezayofThe Advanced Robotic Technologies for Surgery Laboratory, Walker Department of Mechanical Engineering, The University of Texas at Austin, TX, USA.
Alison BarerTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Selena CaoTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Rachael OrkinTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
Farshid AlambeigiThe Advanced Robotic Technologies for Surgery Laboratory, Walker Department of Mechanical Engineering, The University of Texas at Austin, TX, USA.
Johnson V JohnTerasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.

Funding

A Novel Semi-autonomous Surgeon-in-the-loop in situ Robotic Bioprinting System for Functional and Cosmetic Restoration of Volumetric Muscle Loss InjuriesDP2AR082471 · NIAMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ALAMBEIGI, FARSHID · 2022 to 2025
$2.3M
Engineering the open porous nanofibrous microsphere integrated fibrillar hydrogel for the co-delivery of antibacterial and angiogenic agents aimed at the rapid diabetic wound repairR01DK134903 · NIDDK · TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION · PI Johnson Vitharikunnil John · 2023 to 2026
$2.2M
NIAMS NIH HHS DP2 AR082471NIDDK NIH HHS R01 DK134903
6 · The paper itself

Abstract

3D bioprinting has emerged as a transformative technology in tissue engineering, significantly impacting the creation of patient-specific tissues to enhance clinical outcomes. Despite its rapid advancement, translating this technology from bench to bedside remains a critical clinical need. New bioprinting approaches, such as handheld printers or robotic arm-driven in-situ biofabrication techniques, have emerged as promising alternatives. These advancements enable the reconstruction of damaged tissue directly on living anatomical structures, offering adaptability and precise matching to the affected area. The integration of biomaterials, tissue engineering principles, and digital technologies, particularly robotics, has garnered substantial interest from both academic and industrial sectors, highlighting its potential for clinical applications. However, challenges persist, including refining bioink formulations, adjusting mechanical properties, facilitating in situ crosslinking, and accurately mimicking the extracellular matrix. This review explores the cutting-edge frontier of in situ 3D bioprinting for tissue regeneration, utilizing both handheld and robotic arm-assisted 3D printers. It systematically examines the relative advantages, disadvantages, challenges, and prospects of this technology as it transitions from bench side to bed side.

Identifiers

PMID40896112
PMCPMC12396635

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.