ArticleCureus2025
Enhancing Diagnostic Accuracy by Utilizing Regional Cerebral Blood Flow (rCBF) as a Value-Added Variable to Dynamic Contrast-Enhanced Perfusion-Weighted Imaging for Differentiating Radionecrosis From Recurrent Brain Tumour.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To enhance diagnostic accuracy by incorporating relative cerebral blood flow (rCBF) as an additional parameter to dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) variables, thereby enabling the differentiation between radionecrosis and recurrent brain tumours. Materials and methods This study involved 54 patients who had previously undergone treatment for primary cerebral tumours. All participants received radiotherapy and underwent both conventional MRI and DSC-PWI. MRI scans were performed using a 1.5 T closed MRI scanner (MAGNETOM Aera, Siemens Healthineers, Erlangen, Germany), equipped with a 16-channel Head/Neck coil for image acquisition. Several perfusion variables were calculated from DSC-PWI, including rCBF, relative cerebral blood volume (rCBV), relative peak height (rPH), and relative percentage of signal intensity recovery (rPSR). Statistical analyses included ANOVA and receiver operating characteristic (ROC) curve analysis, with histopathological findings used as the reference standard for diagnostic correlation. Results A total of 38 patients (38/54, 70.4%) were diagnosed with tumour recurrence (TR), while 16 patients (16/54, 29.6%) were diagnosed with radionecrosis. The values of rCBF, rCBV, rPSR, and rPH were significantly higher (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.