Evidence map›Paper›PMID 40896072›Full record

ArticleCureus2025

Clinical and Transfusion Approach to Neonatal Thrombocytopenia Associated With Systemic Lupus Erythematosus: A Case Report.

Alejandra G Rosado-Ordaz, Paulina Espadas-Sauri, Victor M Ayuso-Diaz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alejandra G Rosado-OrdazFaculty of Medicine, Universidad Autónoma De Yucatán (UADY), Mérida, MEX.
Paulina Espadas-SauriDepartment of Pediatrics, Institute for Social Security and Services for State Workers (ISSSTE) - Hospital Regional "Elvia Carrillo Puerto", Mérida, MEX.
Victor M Ayuso-DiazResearch and Education Division, Medical Care and Research, Mérida, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune diseases present a clinical challenge for young women of childbearing age since pregnancy can affect their progression and lead to complications for both mother and baby. Systemic lupus erythematosus (SLE) is of particular interest in this context due to its association with an increased risk of spontaneous abortion, foetal death, pre-eclampsia, intrauterine growth restriction, preterm delivery, and various neonatal manifestations, including thrombocytopenia. In this context, autoimmune neonatal thrombocytopenia, caused by the transplacental transfer of maternal autoantibodies, may be the first sign of an undiagnosed autoimmune disease in the mother. This report documents the clinical and transfusion management of severe neonatal thrombocytopenia in a pregnancy involving a mother with a history of idiopathic thrombocytopenic purpura. Subsequent study revealed positive serology for SLE. The favourable outcome for the neonate following intensive management underscores the importance of promptly identifying this condition and adopting a multidisciplinary approach to minimise the risk of severe haemorrhagic complications.

Indexed as

antinuclear antibodiesautoimmune cytopeniaimmune thrombocytopenic purpuramaternal-fetal interfaceneonatal intensive careneonatal lupusneonatal thrombocytopeniapostpartum immunologysystemic lupus erythematosus

Identifiers

PMID40896072
PMCPMC12393008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.