Evidence map›Paper›PMID 40896044›Full record

ArticleCureus2025

Severe and Long-Term Side Effects of Radiotherapy for Nasopharyngeal Cancer: A Case Report.

Mourad Nafaa, Mamoun Lahlou, Amal Miqdadi, Mostapha Noussair, Belyamani Lahcen

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mourad NafaaEmergency Department, Cheikh Khalifa International University Hospital, Casablanca, MAR.
Mamoun LahlouEmergency Department, Mohammed VI University of Health Sciences, Casablanca, MAR.
Amal MiqdadiMedicine Department, Cheikh Khalifa International University Hospital, Casablanca, MAR.
Mostapha NoussairEmergency Department, Cheikh Khalifa International University Hospital, Casablanca, MAR.
Belyamani LahcenEmergency Department, Mohammed V Military Training Hospital, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy is a crucial treatment modality for head and neck cancers, demonstrating significant efficacy in tumor control. However, its application can also lead to challenging complications, particularly due to late effects on healthy tissues. These complications arise from cellular damage, scar fibrosis development, and reduced local blood flow caused by radiation-induced vascular changes. Our patient's experience highlights the diverse range of complications, including trismus, hyposalivation, and visual impairments, commonly associated with radiotherapy in this context. Thus, while radiotherapy is indispensable in cancer management, proactive measures are essential to mitigate its adverse effects and optimize patient outcomes. This case aims to illustrate the possible severe late effects of radiotherapy for nasopharyngeal cancer, emphasizing the need for prolonged surveillance and multidisciplinary management strategies to minimize functional sequelae and improve quality of life in long-term survivors.

Indexed as

complication of treatmentmedical icuradiotherapy (rt)trismusucnt

Identifiers

PMID40896044
PMCPMC12393308

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.