Evidence map›Paper›PMID 40896004›Full record

ArticleCureus2025

A Case Report of a Patient Surviving Severe Acidemia With Arterial pH Less Than 6.5.

Karthik V Iyer, Justin A Jebackumar, Sarah Sundet, Moye Mathew, Vikram Oke

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karthik V IyerInternal Medicine/Critical Care Medicine, Mercy Hospital Jefferson, Festus, USA.
Justin A JebackumarInternal Medicine, Lake Erie College of Osteopathic Medicine, Erie, USA.
Sarah SundetInternal Medicine, Mercy Hospital Jefferson, Festus, USA.
Moye MathewInternal Medicine, Mercy Hospital Jefferson, Festus, USA.
Vikram OkePulmonary and Critical Care, Mercy Medical Center, Festus, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surviving an arterial pH below 6.5 is exceedingly rare due to significant disruption of processes at the cellular level. We report a case of a 25-year-old female with altered mental status, hypotension, and refractory metabolic acidosis. Initial arterial blood gases were unreadable, but aggressive sodium bicarbonate therapy revealed an arterial pH of 6.62. Suspected ethylene glycol poisoning led to aggressive bicarbonate replacement, fomepizole therapy, and emergent hemodialysis. The patient showed rapid clinical recovery and was discharged from the hospital after six days, demonstrating that recovery is possible with appropriate, timely care even at potentially fatal arterial pH levels.

Indexed as

ethylene glycol poisoningfomepizolehemodialysismetabolic acidosissevere acidemia

Identifiers

PMID40896004
PMCPMC12398339

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.