Evidence map›Paper›PMID 40895914›Full record

ArticleCureus2025

A Rare Case of Double True Umbilical Cord Knots With a Nuchal Cord: A Case Report.

Sylvia Dygulski, Riah S Lee, Melissa Lin, Nidhi Chawla, Mason Hui, Sadia Sahabi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylvia DygulskiSurgery, Touro College of Osteopathic Medicine, Middletown, USA.
Riah S LeeSurgery, Touro College of Osteopathic Medicine, Middletown, USA.
Melissa LinObstetrics and Gynecology, Touro College of Osteopathic Medicine, Middletown, USA.
Nidhi ChawlaMedicine and Surgery, Touro College of Osteopathic Medicine, Middletown, USA.
Mason HuiMinimally Invasive Gynecologic Surgery, and Obstetrics and Gynecology, Overlook Medical Center, Summit, USA.
Sadia SahabiObstetrics and Gynecology, Vassar Brothers Medical Center, Poughkeepsie, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A double true umbilical cord knot (TUCK) is a rare complication of pregnancy that is often missed on ultrasonography. The stricture caused by TUCK can lead to occlusion of fetal circulation, fetal asphyxia, and subsequent death. Despite these risks, there is a lack of evidence and no specific consensus on both antepartum and intrapartum management of TUCK. We report a rare case of a healthy male neonate with a double TUCK and nuchal cord delivered vaginally with a vacuum assist. A 26-year-old female, G2P1001, at 39 weeks of gestation, presented to the labor and delivery unit for induction of labor for suspected fetal macrosomia. The labor course was complicated by recurrent variable decelerations during the second stage of labor, which prompted an assisted vaginal delivery. Upon delivery, a single tight nuchal cord was noted, which was successfully reduced. Further examination revealed two TUCKs. Subsequently, the umbilical cord was doubly clamped and cut, and the neonate was transferred to the NICU team for further evaluation. Neonatal and maternal outcomes were reassuring, with no immediate complications observed.  The umbilical cord plays an essential role in transporting nutrients and oxygen to the fetus and discarding waste products. Polyhydramnios, small fetus size, gestational DM, and male fetuses have been reported to be associated with an increased risk of TUCK. Despite advancements in prenatal imaging, true knots remain difficult to detect until delivery. If TUCK remains undiagnosed until delivery, it increases the likelihood of fetal compromise and death. Therefore, close surveillance is warranted in these unusual cases. This case highlights the critical need for monitoring throughout pregnancy, allowing for timely intervention and optimization of maternal and neonatal outcomes.  The coexistence of double TUCK and nuchal cord is a rare complication that is difficult to detect prenatally due to nonspecific imaging findings. In light of the lack of evidence-based treatment options available, we highlight the importance of further research for an accurate prenatal diagnosis of TUCK and to reduce complications and fetal demise.

Indexed as

double true umbilical cord knotfalse umbilical cord knotnuchal cordtrue umbilical cord knotumbilical cord knotumbilical cord true tight knot

Identifiers

PMID40895914
PMCPMC12396611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.