ArticleCureus2025
Endoscopic Submucosal Dissection of Large Gastric Hyperplastic Polyps: Clinicopathological Study From a Single Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Background Gastric hyperplastic polyps (GHPs) represent a subset of gastric polyps that are clinically problematic when large and they can cause persistent, low-grade bleeding or gastric outlet obstruction. Rare malignant transformation has been reported, albeit not in our experience. Methods We retrospectively studied the clinicopathologic characteristics of large GHPs (≥20 mm) excised by endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) between 2013 and 2020 at a single institution. Results Ten patients underwent 37 resections by ESD (n=16), EMR (n=15), and snare resection (SR, n=6). For patients with available follow-up endoscopies, the overall recurrence rate was 9/13 (69.2%) for ESD procedures, 14/14 (100%) for EMR procedures, and 2/2 (100%) for SR procedures, with an average follow-up time of 9.4 months. All cases excised by ESD without recurrence had negative deep and lateral margins. The most common adverse event associated with ESD and EMR is bleeding. Histological examination reveals classic features of gastric hyperplasia, including superficial ulceration, granulation tissue with reactive basal atypia, gastropathy and gastritis-like features. There was one case with intestinal metaplasia, yet none revealed dysplasia or neoplasia and all the studied samples were negative for
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