ArticleCureus2025
Incidence and Clinical Outcomes of Postoperative Acute Kidney Injury in Relation to Etiological Factors and Surgical Procedures.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- A Dynamic Approach to Assessing and Predicting AKI Risk in Patients with Aortoiliac Occlusive Disease Undergoing Aorto-Bifemoral Bypass.Diagnostics (Basel, Switzerland) · 2026Article
- Can Intraoperative Anesthesiological Management Reduce the Risk of Acute Kidney Injury After Liver Transplantation? A Systematic Review.Journal of clinical medicine · 2026Review
- Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivePostoperative acute kidney injury (AKI) is a frequent yet preventable complication linked with increased morbidity, mortality, and healthcare burden. Multiple perioperative risk factors contribute to its development. This study aimed to determine the incidence, clinical outcomes, and independent predictors of postoperative AKI across various surgical procedures.
methodsThis cross-sectional observational study was conducted at the Department of Surgery at a tertiary care hospital between November 2023 and July 2024. A total of 175 adult patients undergoing general surgical procedures under regional or general anesthesia were enrolled using non-probability consecutive sampling. Patients with chronic kidney disease, end-stage renal disease, or pre-existing AKI were excluded. Clinical, laboratory, and intraoperative variables were recorded using a standardized proforma. Data analysis was performed using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States), with multivariable logistic regression applied to identify independent predictors of postoperative AKI.
resultsOut of 175 patients, postoperative AKI occurred in 33 individuals (18.9%), predominantly Stage 1 (63.64%). Patients with AKI were older (61.85 ± 8.51 vs. 56.23 ± 11.33 years, p = 0.008) and had higher baseline serum creatinine (1.12 ± 0.25 vs. 0.99 ± 0.15 mg/dL, p < 0.001). Significant associations with AKI included a medical history of hypertension (75.8%, OR: 6.52, p < 0.001), diabetes (45.5%, OR: 3.11, p = 0.004), ischemic heart disease (24.2%, OR: 3.47, p = 0.010), contrast exposure (24.2%, OR: 5.36, p = 0.001), and nephrotoxic drugs (48.5%, OR: 5.74, p < 0.001). ICU admission (45.5%), dialysis (18.2%), and in-hospital mortality (18.2%) were significantly higher in AKI cases (all p < 0.05).
conclusionPostoperative AKI was significantly linked with adverse outcomes and identifiable clinical and operative risk factors. Focused preventive strategies and early intraoperative risk mitigation may reduce its incidence and improve surgical safety in high-risk patients.
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