ArticleJournal of multimorbidity and comorbidity
Trends and disparities in heart failure and heart failure with obesity mortality among U.S. adults: A 1999-2020 analysis of geographic, gender, and racial variations using CDC WONDER data.
Article in Journal of multimorbidity and comorbidity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Disparities and trends in drug-related adverse reaction mortality in the United States, 1999-2020.Therapeutic advances in drug safety · 2026Article
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart failure (HF) is a leading cause of hospitalization and mortality, and it poses a significant burden on healthcare systems globally. Obesity is a considerable risk factor for HF and contributes to increased cardiac stress and metabolic demands. Methods: Data from the CDC WONDER database were examined from 1999-2020 for HF and HF with obesity-related mortality in adults aged 25 years and older at the time of death, using ICD-10 codes. Age-adjusted mortality rates (AAMR) per million persons were calculated. Results: From 1999 to 2020, the overall AAMR for HF-related deaths in adults declined from 1627 to 1544 (AAPC: -0.49, 95% CI: -0.63 to -0.34), whereas AAMR for HF and obesity rose steadily from 10.7 in 1999 to 42.1 in 2020 (AAPC: 6.23, 95% CI: 5.50 to 6.82). The overall HF-related AAMR for both genders decreased from 1999 to 2020, with a more significant decline in women. In contrast, HF and obesity-related AAMRs significantly increased for both genders, with a more pronounced rise in men. HF-related AAMRs decreased for Whites, Hispanic or Latinos, and Asian/Pacific Islanders but increased statistically insignificantly for Black/African Americans and American Indian/Alaska Natives. HF and obesity-related AAMRs increased across all races from 1999 to 2020, with an overall AAPC of 6.23. The highest HF-associated mortality and HF and obesity-related rates were observed in the Midwest. Conclusion: Overall, a declining trend in HF-related mortality could be seen. However, the increasing HF-obesity mortality despite a general decrease in HF death is concerning.
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