Evidence map›Paper›PMID 40895751›Full record

ArticleRSC advances2025

Synthesis of some new pyrimidine-based pyrene/benzochromene hybrids as EGFR kinase inhibitors in HCT-116 cancer cells through apoptosis.

Yassin Adam A Mohammed, Nabila A Kheder, Mohamed S Nafie, Ashraf A Abbas, Kamal M Dawood

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yassin Adam A MohammedDepartment of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt kmdawood@sci.cu.edu.eg (+202) 35727556 (+202) 35676602.ORCID https://orcid.org/0009-0002-5076-6517
Nabila A KhederDepartment of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt kmdawood@sci.cu.edu.eg (+202) 35727556 (+202) 35676602.ORCID https://orcid.org/0000-0001-5300-9189
Mohamed S NafieDepartment of Chemistry, College of Sciences, University of Sharjah Sharjah 27272 United Arab Emirates.ORCID https://orcid.org/0000-0003-4454-6390
Ashraf A AbbasDepartment of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt kmdawood@sci.cu.edu.eg (+202) 35727556 (+202) 35676602.ORCID https://orcid.org/0000-0001-7061-9907
Kamal M DawoodDepartment of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt kmdawood@sci.cu.edu.eg (+202) 35727556 (+202) 35676602.ORCID https://orcid.org/0000-0002-1351-9886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of new pyrimidine-pyrene hybrids 4, naphtho[1,2-

Identifiers

PMID40895751
PMCPMC12395000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.