Evidence map›Paper›PMID 40895657›Full record

ArticleCureus2025

Comparative Evaluation of Nanosized Intracanal Medicaments on the Penetration and Fracture Resistance of Root Dentin: An In Vitro Study.

Mayakiru Pakyntein, Suchismita Chakraborty, Rubi Kataki, Adrija Deka, Debosmita Roy, Diganta Borah

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mayakiru PakynteinConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.
Suchismita ChakrabortyConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.
Rubi KatakiConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.
Adrija DekaConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.
Debosmita RoyConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.
Diganta BorahConservative Dentistry and Endodontics, Regional Dental College, Guwahati, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of calcium hydroxide (CH) is crucial in the proper disinfection of root canals. However, CH affects the fracture resistance of root dentine and also has limited permeability. Nano-based intracanal medicaments have several benefits over traditional medicaments, including a greater surface area-to-volume ratio and better penetrability. Therefore, this in vitrostudy was performed to evaluate and compare the effect of conventional CH and various nanoparticle-based intracanal medicaments on the penetration and fracture resistance of radicular dentin. MATERIALS AND

methodsOne hundred samples were taken and randomly divided into four (n=20) experimental groups (nano-CH (NCH), nano-chitosan (NCS), NCH + nano-silver (NAg), NCS + NAg, and a control group (CH). At the end of one month, out of the 20 samples from each group, 10 samples were used to assess the fracture resistance in a universal testing machine, and the other 10 samples were used to determine the depth of penetration using a field emission scanning electron microscope.

resultsThe mean fracture resistance of root dentin value was the highest with group II (NCS) and the least in the control group (CH), which was statistically significant. The maximum penetration depth of intracanal medicaments was observed with group III (NCH + NAg) and the least in the control group (CH), which was statistically significant. Among the thirds of the root samples, the highest mean depth of penetration was seen in the coronal third and the least in the apical third in all the groups, which was statistically significant.

conclusionThe resistance to fracture and penetration depth at a four‑week interval were higher in nano forms when compared with conventional CH.

Indexed as

calcium hydroxidechitosannanoparticlesscanning electron microscopesilver

Identifiers

PMID40895657
PMCPMC12398687

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.