ArticleNature reviews. Materials2019
Ingestible Electronics for Diagnostics and Therapy.
Article in Nature reviews. Materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed.
- Minimally invasive bioelectronic implants.Nature materials · 2026Review
- A comprehensive review of thermal ablation technologies for transdermal drug delivery: mechanisms, commercial products, and future smart systems.Drug delivery and translational research · 2026Review
- Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Toward autonomous robotic-assisted and microrobotic surgery.Science advances · 2026Review
- An Edible HAdvanced healthcare materials · 2026Article
- Wearable technologies in clinical trials for drug development: trends and emerging opportunities.Nature reviews. Drug discovery · 2026Review
- Metal anchoring strategy: electrochemical sensor with excellent performance in gastrointestinal secretions.RSC advances · 2026Article
- Microrobotic copper-rich electrochemical interfacing for targeted cancer theranostics in the gut.Science advances · 2026Article
- A Soft-Robotic Biomimetic Benchtop Model for Esophageal Motility Simulation.Nature communications · 2026Article
- Physical Intelligence in Small-Scale Robots and Machines.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Emerging Triboelectric Nanogenerators for In-Body Implantation.Small methods · 2026Review
- Edible electronics: Current landscape and emerging pathways.Journal of materials research · 2026Review
- Soft bioelectronics for wireless drug delivery: programmable, minimally invasive and closed-loop therapeutics.npj soft matter · 2026Review
- Barriers to translating continuous monitoring technologies for preventative medicine.Nature biomedical engineering · 2025Review
- A gastric retentive robotic capsule enables emergency-prepared and responsive oral drug delivery in canine models.Science advances · 2025Article
- Wearable biomolecular sensing nanotechnologies in chronic disease management.Nature nanotechnology · 2025Review
- Article
- Biodegradable ultrasound contrast tape for tracing intestinal motility.Nature communications · 2025Article
- Digital Therapeutics in Cardiovascular Healthcare: A Narrative Review.Current cardiology reports · 2025Review
- Continuous Biochemical Profiling of the Gastrointestinal Tract Using an Integrated Smart Capsule.Nature electronics · 2025Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The gastrointestinal (GI) tract offers the opportunity to detect physiological and pathophysiological signals from the human body. Ingestible electronics can gain close proximity to major organs through the GI tract and therefore, can serve as clinical tools for diagnostics and therapy. In this Review, we summarize physiologic and anatomic characteristics of the GI tract, which present both challenges and opportunities for the development of ingestible devices. We describe recent breakthroughs in material science, electrical engineering, and data science that have permitted exploration of technologies for both sensing and therapy via the GI tract. Novel sensing opportunities include electrochemical, electromagnetic, optical, and acoustic protocols, with capacity to sense luminal or extra-luminal analytes in the GI tract. We review novel therapeutic interventions such as anatomic targeting of drug delivery, enhanced drug delivery including the delivery of macromolecules and potentially the delivery of electrical signals as the therapy. Finally, we investigate major challenges associated with ingestible electronics, including safety, communication, powering, steering and tissue interactions. Ingestible electronics are an exciting arena of scientific innovation and they may pave the way for a novel area in medicine, enabling patients to receive remote, electronically-assisted health care.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.