ArticleInfection and drug resistance2025
Trends and Characteristics of Pertussis Epidemic in Pediatric Patients During and After the COVID-19 Pandemic in East China.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Preliminary epidemiological and clinical profile of the 2024 pediatric pertussis outbreak: a retrospective analysis.Frontiers in pediatrics · 2026Article
- Global disease burden and trends of pertussis in individuals under 20 years old: 1990-2021-insights from the global burden of disease study 2021.Translational pediatrics · 2025Article
- Pertussis resurgence and epidemiology of fully vaccinated cases in eastern China: evidence for vaccination timing.Frontiers in public health · 2025Article
- Clinical characteristics and mortality risk factors among hospitalized infants and children with pertussis in China: a retrospective study.Frontiers in public health · 2025Article
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Authors and funding
10 authors.
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Abstract
Background: Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis, posing a significant health threat to children. Despite vaccination efforts, a resurgence of pertussis has been observed globally, especially during and after the COVID-19 pandemic. This study aims to investigate the epidemiological trends and characteristics of pertussis among pediatric patients during and after the COVID-19 pandemic in East China. Methods: We included 92,300 patients aged 0-18 years with suspected symptoms of pertussis infection from January 1, 2022, to November 30, 2024, in a tertiary children's hospital in China. Clinical information (eg, detection date, date of birth, gender, type of patients) and pertussis test results were extracted from the laboratory information system. We used two independent sample Results: Twenty-two thousand six hundred and forty-two (24.5%) cases were detected as positive cases. Cases surged from November 2023, peaking in April 2024 (n=5363). The highest positive detection rate of pertussis infection was observed in children aged over 6 years (36.2%), particularly among outpatients (37.6%), while the lowest rate was in those aged 18 months to 3 years (12.8%); significant differences were also noted by gender, patient type, season, and COVID-19 pandemic phases ( Conclusion: This study highlights the resurgence of pertussis among children in Eastern China during and after the COVID-19 pandemic, emphasizing significant epidemiological shifts and expanded age susceptibility, underscoring the urgent need for enhanced vaccination strategies and public health interventions.
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