Evidence map›Paper›PMID 40895603›Full record

Article... International Symposium on Medical Robotics. International Symposium on Medical Robotics2025

Cannula-mounted Robots for Semi-autonomous Vertebroplasty: A Comparison of Piezo-based and Screw-based Inchworm Drive Designs.

Michelle J Song, Benjamin D Killeen, Justin D Opfermann, Blanca Inigo, Christopher Bailey, Ali Uneri, Mathias Unberath, Axel Krieger

Abstract read
In one paragraph

Article in ... International Symposium on Medical Robotics. International Symposium on Medical Robotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A Review of Robotic Surgery: Engineering Considerations and Future Directions From Surgeons' Perspectives.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michelle J SongDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Benjamin D KilleenDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Justin D OpfermannDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Blanca InigoDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Christopher BaileyDepartment of Radiology, Johns Hopkins University, Baltimore, MD, USA.
Ali UneriDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Mathias UnberathDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Axel KriegerDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.

Funding

A Multi-robot System for Semi-automated Image-guided Vertebral AugmentationR01EB036341 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Mathias Unberath · 2024 to 2026
$1.5M
NIBIB NIH HHS R01 EB036341
6 · The paper itself

Abstract

Vertebral compression fractures are estimated to affect over 200 million people globally. Percutaneous vertebroplasty is a widely accepted minimally invasive treatment, but it has limitations including prolonged radiation exposure for providers and a steep learning curve. To address these challenges, we present two cannula-mounted robot designs for semi-autonomous, high-precision cannula insertion. Both designs are based on an inchworm mechanism, with one using an amplified piezoelectric actuator and the other using a linear actuator inspired approach. Each design is designed to generate at least 150 N of thrust force with submillimeter accuracy to reliably insert the cannula into the vertebral body. Finite element analysis shows that the material deformations of the baseplates, 42 ± 12 μm for the piezo inchworm design and 7.7±3.2 μm for the screw inchworm design, are substantially lower than the corresponding stroke lengths, confirming the feasibility of generating linear motion. An in silico imaging trial reveals the screw inchworm design's 44.4% smaller surgical footprint enables superior cannula insertion trajectory visualization compared to the piezo inchworm design. These results indicate that while both designs meet clinical design requirements for cannula insertion, the screw inchworm robot is better suited for a semi-autonomous approach to vertebroplasty.

Indexed as

cannula mounted robotpiezo actuatorRobotic surgeryvertebral compression fracturesvertebroplasty

Identifiers

PMID40895603
PMCPMC12395539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.