Evidence map›Paper›PMID 40895587›Full record

ArticleStigma and health2024

Examining the Direct and Mediated Associations Between Perceived Discrimination and Prescription Opioid Misuse Among Individuals with Chronic Pain.

Patricia Timmons, Lakeya S McGill, Rachel V Aaron, Andrew H Rogers, Stephen T Wegener, Claudia M Campbell, Chung Jung Mun

Abstract read
In one paragraph

Article in Stigma and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patricia TimmonsCollege of Health Solutions, Arizona State University.
Lakeya S McGillDepartment of Medicine, University of Pittsburgh School of Medicine.
Rachel V AaronDepartment of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine.
Andrew H RogersDepartment of Anesthesiology and Pain Medicine, University of Washington School of Medicine.
Stephen T WegenerDepartment of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine.
Claudia M CampbellDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine.
Chung Jung MunDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine.

Funding

University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP)K12NS130673 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Daniel J Clauw, Steven Edward Harte · 2022 to 2026
$12.5M
Sleep and circadian rhythm disturbances as risk and progression factors for multiple chronic pain conditionsR01NS129887 · NINDS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Chung Jung Mun · 2023 to 2026
$2.5M
Ethnic differences in endogenous pain regulation: PET imaging of opioid receptorsR01MD009063 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE · 2014 to 2018
$2.1M
Optimizing pain-related outcomes following orthopedic trauma: testing novel risk factors and determining the feasibility of a new pain psychology interventionK23HD104934 · NICHD · JOHNS HOPKINS UNIVERSITY · PI Rachel V. Aaron · 2022 to 2026
$756k
Evaluating dynamic associations between pain catastrophizing and the effect of cannabinoidsF32DA049393 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MUN, CHUNG JUNG · 2019 to 2020
$127k
NHLBI NIH HHS L60 HL170453NICHD NIH HHS K23 HD104934NIDA NIH HHS F32 DA049393NIMHD NIH HHS R01 MD009063NINDS NIH HHS K12 NS130673NINDS NIH HHS R01 NS129887
6 · The paper itself

Abstract

Objective: Experiences of discrimination, a notable psychosocial stressor, are considered an important risk factor for problematic opioid use. We examined whether pain severity, pain interference, anxiety, and depressive symptoms are pathways through which discrimination may be associated with increased prescription opioid misuse behaviors among individuals with chronic pain. Method: A total of 234 participants who reported being prescribed opioids for chronic pain management were included from a parent longitudinal study collected from Amazon's MTurk. Study variables were collected at baseline and 12-month follow-up. Path analyses tested the hypothesized model, with socio-demographic variables and outcomes measured at baseline included as covariates. Mediated effects were examined using percentile bootstrap method. Results: After controlling for socio-demographic covariates, pain severity, pain interference, anxiety, and depressive symptoms, baseline discrimination was significantly associated with greater prescription opioid misuse behaviors ( Conclusions: Discrimination may play an important role in prescription opioid misuse behaviors among individuals with chronic pain. Furthermore, discrimination is a risk factor contributing to elevated anxiety and depressive symptoms, with broad clinical implications for individuals coping with chronic pain. However, pain severity, pain interference, anxiety and depressive symptoms did not emerge as underlying mechanisms that link discrimination and prescription opioid misuse. Replication and extension in future studies are warranted.

Indexed as

anxietydepressiondiscriminationopioid misusepain

Identifiers

PMID40895587
PMCPMC12396542

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.