ReviewFrontiers in immunology2025
Immunobiology roles of the human CD161 receptor in T cells.
Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- NKR-P1A/CD161: A Multifunctional Immune Receptor at the Crossroads of Antitumor Immunity.Biomolecules · 2026Review
- Bovine natural killer cell subsets can be defined by differential expression of CD161 (Frontiers in immunology · 2026Article
- SLECA: A Single-Cell Atlas of Systemic Lupus Erythematosus Enabling Rare-Cell Discovery Using Graph Transformer.Computational and structural biotechnology journal · 2026Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human C-type lectin-like molecule CD161 is a type II transmembrane protein expressed on the surface of various lymphocytes within both the innate and adaptive immune systems. CD161 serves as a marker for innate-like T cells and IL-17-producing cells. However, the meaning of these T cells expressing CD161 has not yet been fully determined. Is CD161 merely a phenotypic marker used to identify T cells that are in a common state of activation and/or lineage? Or does this C-type lectin itself have important effector functions? This article aims to explore the latest research progress on CD161-expressing T cells, particularly human αβTCR+T and γδTCR +T cells, and evaluate the importance of CD161 expression on immune function and human diseases through this research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.