Evidence map›Paper›PMID 40895517›Full record

ArticleDEN open2026

High Score of ELST-Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2-i Index.

Ken Nakamura, Seiji Futagami, Shuhei Agawa, Sakura Higashida, Tomohide Tanabe, Takeshi Onda, Rie Kawawa, Mayu Habiro, Kumiko Kirita, Songyu Sai and 8 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ken NakamuraDivision of Gastroenterology Nippon Medical School Tokyo Japan.ORCID https://orcid.org/0009-0003-5723-1491
Seiji FutagamiDivision of Gastroenterology Nippon Medical School Tokyo Japan.ORCID https://orcid.org/0000-0003-0502-8646
Shuhei AgawaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Sakura HigashidaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Tomohide TanabeDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Takeshi OndaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Rie KawawaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Mayu HabiroDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Kumiko KiritaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Songyu SaiDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Norio ItokawaDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Nobue UekiDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Yoshiyuki WatanabeDepartment of Internal Medicine Kawasaki Rinko General Hospital Kawasaki Japan.
Ryo OhtaDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School Tokyo Japan.
Nobuhiko TaniaiDepartment of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School Tokyo Japan.
Kazufumi HondaDepartment of Bioregulation Graduate School of Medicine Nippon Medical School Tokyo Japan.
Katsuhiko IwakiriDivision of Gastroenterology Nippon Medical School Tokyo Japan.
Masanori AtsukawaDivision of Gastroenterology Nippon Medical School Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To evaluate the usefulness of the ELST-blue score to explore its potential application in identifying high-risk groups for early chronic pancreatitis (ECP) through reflecting on pancreatic elasticity and the reduction of pancreatic function, and we tried to demonstrate whether the ELST-blue score was significantly associated with apolipoprotein A2 (apoA2) isoforms in patients with ECP. Methods: Forty-four patients with pancreatic enzyme abnormalities underwent endosonography. We divided two groups, one group was patients with ECP ( Results: Epigastric pain tended to be more severe in patients with ECP than in those without ECP. There was a significant difference in the diameter of the main pancreatic duct of more than 2 mm as well as in stranding or hyperechoic foci and lobularity between patients with ECP and non-ECP. The ELST-blue score was significantly higher in patients with ECP than in non-ECP ( Conclusions: Patients with ECP accompanied by a high score of ELST-blue have to be followed up carefully.

Indexed as

apolipoprotein A2 | early chronic pancreatitis | elastography | endosonography | exocrine pancreatic function

Identifiers

PMID40895517
PMCPMC12395273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.