Evidence map›Paper›PMID 40895496›Full record

ArticleJCEM case reports2025

Glycemic Derangements With Capivasertib-From Hyperglycemia to Diabetic Ketoacidosis: A Report of 3 Cases.

Sophie Nicolich-Henkin, Lauren Waters, Neha Bansal, Stanislaw Klek

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophie Nicolich-HenkinDivision of Endocrinology, NYU Long Island School of Medicine, Mineola, NY 11501, USA.ORCID https://orcid.org/0009-0004-4015-487X
Lauren WatersDivision of Endocrinology, NYU Long Island School of Medicine, Mineola, NY 11501, USA.
Neha BansalDivision of Endocrinology, NYU Long Island School of Medicine, Mineola, NY 11501, USA.
Stanislaw KlekDivision of Endocrinology, NYU Long Island School of Medicine, Mineola, NY 11501, USA.ORCID https://orcid.org/0000-0001-8589-9673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capiversatib is a pan-Ak strain transforming inhibitor used in combination with fulvestrant for the treatment of hormone receptor-positive advanced breast cancer and has a known adverse effect of hyperglycemia. We present 3 cases of severe hyperglycemia, 2 of which presented as diabetic ketoacidosis, in patients being treated with capivasertib. These cases demonstrate the severity of hyperglycemia that can result from capivasertib use, as well as highlight treatment regimens and patient outcomes.

Indexed as

capivasertibdiabetic ketoacidosisinsulin resistance

Identifiers

PMID40895496
PMCPMC12395548

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.