ArticleFrontiers in microbiology2025
Epidemiology of enterotoxigenic
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- One Health Perspective on the EnterotoxigenicMicroorganisms · 2026Review
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Enterotoxigenic Methods: Using a cross-sectional design, we recruited 387 children under five years of age with acute diarrhea. Total nucleic acid (TNA) was extracted from stool samples and analyzed using a PCR-based customized TaqMan Array Card (TAC), which included three ETEC toxin genes (LT, STh, and STp) and six ETEC colonization factors (CFs). A structured questionnaire was employed to collect participants information. Findings: ETEC was detected in 148/387 samples, yielding a prevalence of 38.2% (95% CI: 34.2-42.2%). Both heat-labile and heat-stable (LT/ST) enterotoxin genes were the most common (43%) followed by heat-labile (30%), and heat-stable (27%). Colonization factors (CF) were present in 52% (77/148) of ETEC-positive samples with CS6 being the most frequently detected CF at 36.3% (28/77). Children aged 13-24 months had significantly elevated odds of infection (aOR = 2.48; 95% CI: 1.36-4.52, Conclusion: These findings highlight the urgent need for targeted public health interventions, including improved sanitation and hygiene practices and vaccine introduction, to mitigate the burden of ETEC-related diarrhea among high-risk populations in disease endemic settings.
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