Evidence map›Paper›PMID 40895307›Full record

ArticleFrontiers in cellular and infection microbiology2025

Comprehensive molecular epidemiology of BVDV in yaks (

Zhi Li, Yuan Han, Yong Fu, Qing Yuan, Shuqin Wang, Xingye Pan, Wanchao Xue, Hong Yin, Shandian Gao, Ru Meng

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhi LiQinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, China.
Yuan HanQinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, China.
Yong FuQinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, China.
Qing YuanQinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, China.
Shuqin WangXining Animal Disease Prevention and Control Center, Xining, China.
Xingye PanAnimal Husbandry and Veterinary Station of Huangyuan County, Xining, China.
Wanchao XueAnimal Husbandry and Veterinary Station of Huangyuan County, Xining, China.
Hong YinGansu Province Research Center for Basic Disciplines of Pathogen Biology, State Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Shandian GaoGansu Province Research Center for Basic Disciplines of Pathogen Biology, State Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Ru MengXining Animal Disease Prevention and Control Center, Xining, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bovine viral diarrhea virus (BVDV) is a major pathogen affecting livestock health in China. However, the current epidemiological status in yaks ( Methods: In the present study, a comprehensive serological and molecular investigation of BVDV in yaks was conducted across broad geographic areas of eight administrative regions including Yushu, Guoluo, Huangnan, Hainan, Haidong, Haixi, Haibei, and Xining in Qinghai Province. Results: The results revealed widespread BVDV exposure in Qinghai yak, with an overall antibody prevalence of 84.52% (1158/1370) and substantial herd variation (12.00~98.07%). Active infections were confirmed through antigen detection, revealing prevalence ranging from 0.34% (Haixi) to 4.90% (Huangnan). Genetic characterization identified two circulating subgenotypes: BVDV-1a (n=3) and the predominant BVDV-1u (n=30), with the latter dominating across all regions. Discussion: These results highlight the endemic circulation of BVDV in Qinghai yak populations and uncover unexpected genetic diversity, emphasizing the need for control measures to mitigate the adverse impacts of BVDV infection in yaks in high-altitude pastoral systems.

Indexed as

Bovine Virus Diarrhea-Mucosal DiseaseDiarrhea Virus 1, Bovine ViralDiarrhea Viruses, Bovine ViralAnimalsAntibodies, ViralCattleChinaGenotypeMolecular EpidemiologyPhylogenyPrevalenceSeroepidemiologic StudiesAntibodies, ViralBovine Viral Diarrhea Virusphylogenetic analysisprevalencesubgenotypesyak (Bos grunniens)

Identifiers

PMID40895307
PMCPMC12391088

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.