ArticleFrontiers in cellular and infection microbiology2025
Combination of nucleated red blood cells and inflammatory biomarkers (PCT and CRP) for predicting sepsis and septic shock in children.
Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development and validation of a prognostic nomogram model for 28-day mortality based on IP-10 and clinical parameters in septic patients in the emergency department.Frontiers in cellular and infection microbiology · 2026Article
- Prognostic role of creatine kinase-MB in elderly patients with sepsis.European journal of medical research · 2025Article
- Commentary: Combination of nucleated red blood cells and inflammatory biomarkers (PCT and CRP) for predicting sepsis and septic shock in children.Frontiers in cellular and infection microbiology · 2025Article
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7 authors.
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Abstract
Introduction: Sepsis remains a leading cause of mortality and morbidity worldwide. This study aimed to investigate the clinical characteristics of children with sepsis and septic shock, with emphasis to evaluate the predictive value of C-reactive protein (CRP), procalcitonin (PCT), and nucleated red blood cell (NRBC) count in pediatric sepsis and septic shock patients. Methods: We included a total of 121 children, including 80 with sepsis and 41 with septic shock, who were admitted to the Children's Hospital of Chongqing Medical University between January 2021 and June 2024. Results: No significant differences in sex, age, weight, or basic diseases were observed between the sepsis and septic shock groups ( Conclussion: The inclusion of the NRBC count, combined with CRP and PCT, significantly increases the predictive efficacy of disease severity or progression, particularly indicative of septic shock, highlighting the potential of this combination for early diagnosis and management in pediatric patients.
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