ArticlePeerJ2025
Impact of fructooligosaccharides on gut microbiota composition and metabolite production: implications for childhood obesity.
Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Short-Chain Inulin and Inulin Neoseries Oligosaccharides from Red Onions Enrich Beneficial Gut Taxa and Attenuate Obesity-Related Outcomes in a Rat Model.Foods (Basel, Switzerland) · 2026Article
- Production and functional applications of fructooligosaccharides and their core bioactive components.World journal of microbiology & biotechnology · 2026Review
- Gut microbiota-immune crosstalk in childhood and adolescent obesity: mechanistic insights and therapeutic potential focused on short-chain fatty acids and emerging metabolites.Frontiers in microbiology · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Contemporary dietary habits in children have been linked to various health issues, particularly the increasing prevalence of childhood obesity. However, the complex relationship between children's diets, gut microbiota, and health outcomes remains incompletely understood. This study investigates the effects of fructooligosaccharides (FOS) on gut microbiota composition and metabolic processes in children, and explores their potential impact on pediatric health outcomes such as obesity and metabolic disorders. Methods: Fecal samples from 39 children (19 boys, 20 girls) aged 6-15 were subjected to Results: FOS supplementation significantly altered the Conclusions: This study highlights changes in microbial structure, metabolite production, potential biomarkers, and altered metabolic pathways following FOS intervention. These findings provide valuable insights into the complex relationship between diet and gut microbiota in obese children and suggest that dietary interventions may influence pediatric health through modulation of the gut microbiome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.