Evidence map›Paper›PMID 40894931›Full record

ArticleFrontiers in cell and developmental biology2025

Identification of plasma lipid metabolism and potential biomarkers in patients with different coronary occlusive acute myocardial infarction.

Hao Chen, Qingyi Zhang, Ai Zhou, Li Zhang, Xing Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao Chen *Department of Cardiology, Wuxi No. 2 People's Hospital of Jiangnan University Medical Center, Wuxi, Jiangsu, China.
Qingyi Zhang *Department of Cardiology, Affiliated Changzhou Children's Hospital of Nantong University, Changzhou, China.
Ai ZhouDepartment of Cardiology, Wuxi No. 2 People's Hospital of Jiangnan University Medical Center, Wuxi, Jiangsu, China.
Li ZhangHongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xing LiDepartment of Cardiology, Wuxi No. 2 People's Hospital of Jiangnan University Medical Center, Wuxi, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myocardial infarction (AMI) is the main cause of death worldwide. We aim to compare the differences in plasma lipid metabolites between AMI patients and normal controls to search for biomarker molecules for AMI with different infarct sites. We enrolled 12 patients in Group A (left coronary artery occlusion), 15 in Group B (right coronary artery occlusion), and 14 in Group C (normal controls) from June 2020 to June 2021. Non-targeted lipidomic analysis was performed and a total of 93 differential lipid molecules were identified. Diagnostic efficiency was evaluated by receiver operating curve. Compared with Group C, there were nine lipid molecules with AUC>0.8 in Groups A and B. Compared with Group B, Group A had six lipid molecules with AUC>0.8. These lipid molecules belonged to the LPC, PC, TG, and DG classes. We focused on LPC (20:4) as a biomarker in AMI.

Indexed as

lipid moleculeslipidomiclysophosphatidylcholinesmyocardial infarctionphosphatidylcholine

Identifiers

PMID40894931
PMCPMC12391077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.