ReviewiScience2025
The role of taurine in bone metabolism.
Review in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Insights into taurine therapy for periodontitis: Targeting osteocyte ferroptosis to mitigate obesity-exacerbated bone damage.Redox biology · 2026Article
- Deficiency of Natural Plant-Derived Gut Metabolites Is a Potential Cause of Skeletal Deformities in Captive-Bred Green Peafowl (Animals : an open access journal from MDPI · 2026Article
- Immune reprogramming in the bone marrow microenvironment: a new perspective on the bone immune microenvironment of postmenopausal osteoporosis.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone metabolism is a dynamic process involving remodeling and rebuilding bone tissue. Important participants in this process include osteoblasts and osteoclasts, which may promote bone formation and bone resorption, respectively. Cumulative evidence suggests that taurine, a sulfur-containing nonessential amino acid, can regulate bone formation, bone resorption, and bone immunity through anti-inflammatory and antioxidant properties in bone metabolic diseases. However, the potential mechanisms by which taurine regulates bone metabolism remain unclear. This review focuses on the potential role of taurine in bone metabolic diseases, particularly osteoporosis and rheumatoid arthritis. Moreover, the regulatory mechanisms of taurine on bone formation, bone resorption, and bone immunity are summarized, which provides a theoretical basis for the application of taurine as a therapeutic agent to improve bone metabolic diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.