Evidence map›Paper›PMID 40894888›Full record

ArticleiScience2025

Global and local nature of cortical slow waves.

Javier Alegre-Cortés, Maurizio Mattia, María Sáez, Ramón Reig

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Javier Alegre-CortésInstituto de Neurociencias CSIC-UMH, Alicante, Spain.
Maurizio MattiaNational Center for Radiation Protection and Computational Physics, Istituto Superiore di Sanità, 00161 Rome, Italy.
María SáezInstituto de Neurociencias CSIC-UMH, Alicante, Spain.
Ramón ReigInstituto de Neurociencias CSIC-UMH, Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Explaining the macroscopic activity of a neuronal population from its microscopic properties poses a great challenge, not just because of the many local agents that play a role, but due to the impact of long-range connections from other brain regions. We used a computational model to explore how local and global components of a network shape the slow wave activity (SWA). A sensitivity analysis allowed us to explore how local properties and long-range connections shaped the SWA of a population and its neighbors. We show that while manipulations in the synaptic excitatory/inhibitory balance can create local changes, cellular components that modulate the excitability or adaptation led to changes in neighboring populations too. We also show

Indexed as

Computer scienceNeuroscienceSystems biology

Identifiers

PMID40894888
PMCPMC12397934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.