Evidence map›Paper›PMID 40894851›Full record

ReviewCJC open2025

Sex-Specific Disparities in the Female Vs Male Patient Population in Left Ventricular Assist Device Use.

Stefanie Marek-Iannucci, Estefania Oliveros, Francesco Fedele, Indranee N Rajapreyar

Abstract readReview
In one paragraph

Review in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefanie Marek-IannucciDepartment of Advanced Heart Failure and Transplant Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Estefania OliverosDepartment of Advanced Heart Failure and Transplant Cardiology, Temple University, Philadelphia, Pennsylvania, USA.
Francesco FedeleDepartment of Cardiovascular Diseases, Policlinico Umberto I, La Sapienza University of Rome Department, Cassino, Rome, Italy.
Indranee N RajapreyarDepartment of Advanced Heart Failure and Transplant Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women remain severely underrepresented in clinical trials, leading to a significant disparity in clinical care and outcome among male vs female patients with advanced heart failure (HF). Sex-specific disparities regarding the etiology of HF, time to diagnosis, severity of disease at time of index hospitalization, response to treatment, and treatment options, including use of temporary or durable mechanical circulatory support devices, may affect women unfavourably. Lack of knowledge regarding sex-specific complications has had an impact on the overall higher mortality level in women vs men. Increasing the awareness regarding this sex-specific imbalance is imperative. The inclusion of women in clinical mechanical circulatory support trials is critical, to improve female patient outcomes in stage D HF with reduced ejection fraction.

Identifiers

PMID40894851
PMCPMC12399135

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.